Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetVasopressin V2 receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Co., Ltd

LigandPNGBDBM35715(benzazepine derivative, 13a)copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 7.4 T: 2°CAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957JRPubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Otsuka Pharmaceutical Co., Ltd

LigandPNGBDBM35715(benzazepine derivative, 13a)copy SMILEScopy InChI
Affinity DataIC50: 64nMpH: 7.4 T: 2°CAssay Description:After reaching confluence in 12-well or 24-well dishes, the cells were washed twice with ice-cold PBS and incubated for 2 hr with [3H]-AVP at 4 deg C...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W957JRPubMed