Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 10 hits in this display
BDBM572327((3S)-N-methyl-1-(3- pyrimidin-5-yl-1H- pyrrolo[2,3...)copy SMILES
BDBM572327((3S)-N-methyl-1-(3- pyrimidin-5-yl-1H- pyrrolo[2,3...)copy SMILES
Ki: 2.93nMAssay Description:MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...More data for this Ligand-Target Pair
BDBM572352(N-methyl-1-(3-pyrimidin- 5-yl-1H-pyrrolo[2,3- b]py...)copy SMILES
Ki: 4.10nMAssay Description:MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...More data for this Ligand-Target Pair
BDBM572390((3R)-N-methyl-1-(3- pyrimidin-5-yl-1H- pyrrolo[2,3...)copy SMILES
Ki: 10.5nMAssay Description:MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...More data for this Ligand-Target Pair
BDBM572390((3R)-N-methyl-1-(3- pyrimidin-5-yl-1H- pyrrolo[2,3...)copy SMILES
Ki: 248nMAssay Description:MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...More data for this Ligand-Target Pair
BDBM572352(N-methyl-1-(3-pyrimidin- 5-yl-1H-pyrrolo[2,3- b]py...)copy SMILES
Ki: 314nMAssay Description:MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...More data for this Ligand-Target Pair
BDBM572352(N-methyl-1-(3-pyrimidin- 5-yl-1H-pyrrolo[2,3- b]py...)copy SMILES
Ki: 360nMAssay Description:MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...More data for this Ligand-Target Pair
BDBM572390((3R)-N-methyl-1-(3- pyrimidin-5-yl-1H- pyrrolo[2,3...)copy SMILES
Ki: 379nMAssay Description:MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...More data for this Ligand-Target Pair
BDBM572327((3S)-N-methyl-1-(3- pyrimidin-5-yl-1H- pyrrolo[2,3...)copy SMILES
Ki: 545nMAssay Description:MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...More data for this Ligand-Target Pair
BDBM572327((3S)-N-methyl-1-(3- pyrimidin-5-yl-1H- pyrrolo[2,3...)copy SMILES
Ki: 5.07E+4nMAssay Description:MRCKα, MRCKβ, ROCK1 and ROCK2 assays were performed using an IMAP fluorescence polarization assay format (Molecular Devices Inc.). 8-12 nM ...More data for this Ligand-Target Pair