Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetVasopressin V1a receptor(Homo sapiens (Human))
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM477635(6-Fluoro-3-(1-(5-(methoxymethyl)-4-(6-methoxypyrid...)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+4nMAssay Description:V1aR: The inhibition effect of the compounds of the present invention on the activity of human V1 aR protein expressed in HEK293/human V1aR stably tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CJ8HMVUS Patent
TargetVasopressin V2 receptor(Homo sapiens (Human))
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM477635(6-Fluoro-3-(1-(5-(methoxymethyl)-4-(6-methoxypyrid...)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+4nMAssay Description:V2R: The inhibition effect of the compounds of the present invention on the activity of human V2R protein expressed in HEK293/human V2R cells was det...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CJ8HMVUS Patent
TargetVasopressin V1b receptor(Homo sapiens (Human))
Jiangsu Hengrui Medicine Co., Ltd.; Shanghai Hengrui Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM477635(6-Fluoro-3-(1-(5-(methoxymethyl)-4-(6-methoxypyrid...)copy SMILEScopy InChI
Affinity DataIC50: 2.58E+4nMAssay Description:V1bR: The inhibition effect of the compounds of the present invention on the activity of human V1bR protein expressed in HEK293/human V1bR cells was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CJ8HMVUS Patent