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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Vasopressin V1a receptor
(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by
ChEMBL
Ligand
BDBM50319797
((4-(benzo[b]thiophen-3-yl)-3-methoxyphenyl)((1S,5R...)
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Affinity Data
Ki: 0.790nM
Assay Description:
Displacement [3H]Arg human recombinant Vasopressin V1a receptor
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24F1QW2
PubMed
Target
Vasopressin V2 receptor
(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by
ChEMBL
Ligand
BDBM50319797
((4-(benzo[b]thiophen-3-yl)-3-methoxyphenyl)((1S,5R...)
copy SMILES
copy InChI
Affinity Data
Ki: 15nM
Assay Description:
Displacement [3H]Arg human recombinant Vasopressin V2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24F1QW2
PubMed
Target
Vasopressin V1a receptor
(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by
ChEMBL
Ligand
BDBM50319797
((4-(benzo[b]thiophen-3-yl)-3-methoxyphenyl)((1S,5R...)
copy SMILES
copy InChI
Affinity Data
IC50: 41nM
Assay Description:
Antagonist activity at human Vasopressin V1a receptor assessed as inhibition of intracellular calcium mobilization by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24F1QW2
PubMed
Target
Vasopressin V2 receptor
(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by
ChEMBL
Ligand
BDBM50319797
((4-(benzo[b]thiophen-3-yl)-3-methoxyphenyl)((1S,5R...)
copy SMILES
copy InChI
Affinity Data
IC50: 838nM
Assay Description:
Antagonist activity at human Vasopressin 2 receptor assessed as inhibition of intracellular cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q24F1QW2
PubMed