Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50319797((4-(benzo[b]thiophen-3-yl)-3-methoxyphenyl)((1S,5R...)copy SMILEScopy InChI
Affinity DataKi:  0.790nMAssay Description:Displacement [3H]Arg human recombinant Vasopressin V1a receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1QW2PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50319797((4-(benzo[b]thiophen-3-yl)-3-methoxyphenyl)((1S,5R...)copy SMILEScopy InChI
Affinity DataKi:  15nMAssay Description:Displacement [3H]Arg human recombinant Vasopressin V2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1QW2PubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50319797((4-(benzo[b]thiophen-3-yl)-3-methoxyphenyl)((1S,5R...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Antagonist activity at human Vasopressin V1a receptor assessed as inhibition of intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1QW2PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50319797((4-(benzo[b]thiophen-3-yl)-3-methoxyphenyl)((1S,5R...)copy SMILEScopy InChI
Affinity DataIC50: 838nMAssay Description:Antagonist activity at human Vasopressin 2 receptor assessed as inhibition of intracellular cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1QW2PubMed