Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398743(CHEMBL2179631)copy SMILEScopy InChI
Affinity DataEC50:  80nMAssay Description:Positive allosteric modulation activity at rat mGlu2R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9D78PubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398743(CHEMBL2179631)copy SMILEScopy InChI
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu8R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9D78PubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398743(CHEMBL2179631)copy SMILEScopy InChI
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu7R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9D78PubMed
TargetMetabotropic glutamate receptor 1(RAT)
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398743(CHEMBL2179631)copy SMILEScopy InChI
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu1R expressed in HEK293 cells co-expressing GIRK channels by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9D78PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398743(CHEMBL2179631)copy SMILEScopy InChI
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu5R expressed in HEK293 cells co-expressing GIRK channels by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9D78PubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398743(CHEMBL2179631)copy SMILEScopy InChI
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu4R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9D78PubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50398743(CHEMBL2179631)copy SMILEScopy InChI
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at rat mGlu6R expressed in HEK293 cells co-expressing GIRK channels by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9D78PubMed