Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 6 hits in this display
BDBM284001(E27 | US10023564, Example 27)copy SMILES
BDBM284001(E27 | US10023564, Example 27)copy SMILES
IC50: 400nMAssay Description:Inhibition of GRK2 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
BDBM284001(E27 | US10023564, Example 27)copy SMILES
IC50: 2.40E+3nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
BDBM284001(E27 | US10023564, Example 27)copy SMILES
IC50: 2.80E+3nMAssay Description:Inhibition of GRK5 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
BDBM284001(E27 | US10023564, Example 27)copy SMILES
IC50: 1.40E+4nMpH: 7.0Assay Description:GRK1, 2 and 5 kinetic assays were conducted in a buffer containing 20 mM HEPES pH 7.0, 5 μM ATP, 2 mM MgCl2, and 0.025% DDM with 50 nM GRK and e...More data for this Ligand-Target Pair
BDBM284001(E27 | US10023564, Example 27)copy SMILES
IC50: 1.60E+4nMAssay Description:Inhibition of GRK1 (unknown origin) preincubated for 10 mins followed by peptide substrate and ATP addition measured after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair