Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50330873(CHEMBL1277786 | US9090589, 4 | trans rac-N1-(4-((6...)copy SMILEScopy InChI
Affinity DataKi:  88nMAssay Description:Inhibition of mouse recombinant iNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC61FTPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Northwestern University; The Regents of the University of California

US Patent
LigandPNGBDBM50330873(CHEMBL1277786 | US9090589, 4 | trans rac-N1-(4-((6...)copy SMILEScopy InChI
Affinity DataKi:  880nMAssay Description:Recombinant NOS isozymes over-expressed in E. coli were utilized. (Ji, H., et al., Discovery of highly potent and selective inhibitors of neuronal ni...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR4VW7US Patent
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50330873(CHEMBL1277786 | US9090589, 4 | trans rac-N1-(4-((6...)copy SMILEScopy InChI
Affinity DataKi:  1.82E+4nMAssay Description:Inhibition of rat recombinant nNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC61FTPubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Northwestern University; The Regents of the University of California

US Patent
LigandPNGBDBM50330873(CHEMBL1277786 | US9090589, 4 | trans rac-N1-(4-((6...)copy SMILEScopy InChI
Affinity DataKi:  1.82E+4nMAssay Description:Recombinant NOS isozymes over-expressed in E. coli were utilized. (Ji, H., et al., Discovery of highly potent and selective inhibitors of neuronal ni...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR4VW7US Patent
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50330873(CHEMBL1277786 | US9090589, 4 | trans rac-N1-(4-((6...)copy SMILEScopy InChI
Affinity DataKi:  1.24E+5nMAssay Description:Inhibition of bovine recombinant eNOSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC61FTPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Northwestern University; The Regents of the University of California

US Patent
LigandPNGBDBM50330873(CHEMBL1277786 | US9090589, 4 | trans rac-N1-(4-((6...)copy SMILEScopy InChI
Affinity DataKi:  1.24E+5nMAssay Description:Recombinant NOS isozymes over-expressed in E. coli were utilized. (Ji, H., et al., Discovery of highly potent and selective inhibitors of neuronal ni...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR4VW7US Patent