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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
University of Liège
Curated by
ChEMBL
Ligand
BDBM50188609
(CHEMBL209245 | N-benzyl-N'-[2-(4-methylphenylamino...)
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Affinity Data
IC50: 1.17nM
Assay Description:
Displacement of [3H]SQ29,548 from TPbeta receptor (long isoform) expressed in COS7 cells at 1 uM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2X63MJT
PubMed
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
University of Liège
Curated by
ChEMBL
Ligand
BDBM50188609
(CHEMBL209245 | N-benzyl-N'-[2-(4-methylphenylamino...)
copy SMILES
copy InChI
Affinity Data
IC50: 1.90nM
Assay Description:
Displacement of [3H]SQ29,548 from TPalpha receptor (short isoform) expressed in COS7 cells at 1 uM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2X63MJT
PubMed
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
University of Liège
Curated by
ChEMBL
Ligand
BDBM50188609
(CHEMBL209245 | N-benzyl-N'-[2-(4-methylphenylamino...)
copy SMILES
copy InChI
Affinity Data
IC50: 45.0nM
Assay Description:
Activity at TPbeta (long isoform) receptor expressed in HEK293 cells assessed as ability to antagonize U46619-mediated calcium ion mobilization
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2X63MJT
PubMed
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
University of Liège
Curated by
ChEMBL
Ligand
BDBM50188609
(CHEMBL209245 | N-benzyl-N'-[2-(4-methylphenylamino...)
copy SMILES
copy InChI
Affinity Data
IC50: 64.5nM
Assay Description:
Activity at TPalpha (short isoform) receptor expressed in HEK293 cells assessed as ability to antagonize U46619-mediated calcium ion mobilization
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2X63MJT
PubMed