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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
15
hits in this display
Target
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50145198
(CHEMBL3765778)
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Affinity Data
Ki: 1.90E+3nM
Assay Description:
Positive allosteric modulation of 5-HT2B receptor (unknown origin)
More data for this Ligand-Target Pair
Target Info
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antibodypedia
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Ligand Info
CHEMBL
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In Depth
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Article
BindingDB Entry DOI:
10.7270/Q2NV9M4S
PubMed
Target
Platelet-activating factor receptor
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50145198
(CHEMBL3765778)
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Affinity Data
Ki: 2.00E+3nM
Assay Description:
Positive allosteric modulation of platelet-activating factor receptor (unknown origin)
More data for this Ligand-Target Pair
Target Info
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KEGG
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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In Depth
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Article
BindingDB Entry DOI:
10.7270/Q2NV9M4S
PubMed
Target
Metabotropic glutamate receptor 4
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50145198
(CHEMBL3765778)
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Affinity Data
EC50: >3.00E+4nM
Assay Description:
Positive allosteric modulation of mGluR4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2NV9M4S
PubMed
Target
Metabotropic glutamate receptor 3
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50145198
(CHEMBL3765778)
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copy InChI
Affinity Data
EC50: >3.00E+4nM
Assay Description:
Positive allosteric modulation of mGluR3 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2NV9M4S
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50145198
(CHEMBL3765778)
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copy InChI
Affinity Data
EC50: 213nM
Assay Description:
Positive allosteric modulation of rat mGluR2 by GTP-gamma-S binding assay
More data for this Ligand-Target Pair
Target Info
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antibodypedia
GoogleScholar
Ligand Info
CHEMBL
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PC sid
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In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2NV9M4S
PubMed
Target
Metabotropic glutamate receptor 6
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50145198
(CHEMBL3765778)
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copy InChI
Affinity Data
EC50: >3.00E+4nM
Assay Description:
Positive allosteric modulation of mGlu6 receptor (unknown origin)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2W95C3K
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50145198
(CHEMBL3765778)
copy SMILES
copy InChI
Affinity Data
EC50: 25nM
Assay Description:
Positive allosteric modulation of recombinant rat mGluR2 preincubated for 5 mins followed by stimulation with EC20 concentration of glutamate for 3 m...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2NV9M4S
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50145198
(CHEMBL3765778)
copy SMILES
copy InChI
Affinity Data
EC50: 61nM
Assay Description:
Positive allosteric modulation of recombinant human mGluR2 expressed in CHO cells preincubated for 5 mins followed by stimulation with EC20 concentra...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2NV9M4S
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50145198
(CHEMBL3765778)
copy SMILES
copy InChI
Affinity Data
EC50: 63nM
Assay Description:
Positive allosteric modulation of recombinant human mGlu2 receptor expressed in CHO cells assessed as potentiation of glutamate-induced effect preinc...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2W95C3K
PubMed
Target
Metabotropic glutamate receptor 3
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50145198
(CHEMBL3765778)
copy SMILES
copy InChI
Affinity Data
EC50: >3.00E+4nM
Assay Description:
Positive allosteric modulation of mGlu3 receptor (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2W95C3K
PubMed
Target
Metabotropic glutamate receptor 4
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50145198
(CHEMBL3765778)
copy SMILES
copy InChI
Affinity Data
EC50: >3.00E+4nM
Assay Description:
Positive allosteric modulation of mGlu4 receptor (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2W95C3K
PubMed
Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50145198
(CHEMBL3765778)
copy SMILES
copy InChI
Affinity Data
EC50: >3.00E+4nM
Assay Description:
Positive allosteric modulation of mGlu5 receptor (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2W95C3K
PubMed
Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50145198
(CHEMBL3765778)
copy SMILES
copy InChI
Affinity Data
EC50: >3.00E+4nM
Assay Description:
Positive allosteric modulation of mGluR5 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2NV9M4S
PubMed
Target
Metabotropic glutamate receptor 6
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50145198
(CHEMBL3765778)
copy SMILES
copy InChI
Affinity Data
EC50: >3.00E+4nM
Assay Description:
Positive allosteric modulation of mGluR6 (unknown origin)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2NV9M4S
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM50145198
(CHEMBL3765778)
copy SMILES
copy InChI
Affinity Data
EC50: 600nM
Assay Description:
Positive allosteric modulation of human mGluR2 by GTP-gamma-S binding assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2NV9M4S
PubMed