Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetVasopressin V1a receptor(Homo sapiens (Human))
Astellas Pharma Inc.

LigandPNGBDBM35675(5H-1-benzazepin-5-ylidene acetamide, 1c)copy SMILEScopy InChI
Affinity DataKi:  15nM ΔG°:  -44.7kJ/moleT: 2°CAssay Description:Chinese hamster ovary (CHO) cells stably expressing human V1a receptors. Cells were washed with phosphate buffered saline, and then collected in ice-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6GQMPubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Astellas Pharma Inc.

LigandPNGBDBM35675(5H-1-benzazepin-5-ylidene acetamide, 1c)copy SMILEScopy InChI
Affinity DataKi:  20nM ΔG°:  -43.6kJ/molepH: 7.4 T: 2°CAssay Description:The affinities of test compounds for human V2 receptor were evaluated by the radioligand binding study using membrane fractions isolated from CHO cel...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6GQMPubMed