Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Astex

LigandPNGBDBM50014711(CHEMBL3262020 | US10759791, Compound 5S | US995101...)copy SMILEScopy InChI
Affinity DataKi:  903nMAssay Description:The NOSs isoform assays involved subjecting 3-8 to an oxyhemoglobin NO capture assay using a Biotek Gen5™ microplate reader. IC50 values for each com...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50014711(CHEMBL3262020 | US10759791, Compound 5S | US995101...)copy SMILEScopy InChI
Affinity DataKi:  903nMAssay Description:Inhibition of purified rat nNOS assessed as inhibition of nitric oxide-mediated oxidation of hemoglobin-A by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50014711(CHEMBL3262020 | US10759791, Compound 5S | US995101...)copy SMILEScopy InChI
Affinity DataKi:  903nMAssay Description:Enzyme inhibition was evaluated by measuring NO production with the hemoglobin capture assay, which was performed with purified NOSs in 96-well plate...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50014711(CHEMBL3262020 | US10759791, Compound 5S | US995101...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of purified mouse iNOS assessed as inhibition of nitric oxide-mediated oxidation of hemoglobin-A by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6S26PubMed
TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Astex

LigandPNGBDBM50014711(CHEMBL3262020 | US10759791, Compound 5S | US995101...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:The NOSs isoform assays involved subjecting 3-8 to an oxyhemoglobin NO capture assay using a Biotek Gen5™ microplate reader. IC50 values for each com...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21N83G1US Patent
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50014711(CHEMBL3262020 | US10759791, Compound 5S | US995101...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Enzyme inhibition was evaluated by measuring NO production with the hemoglobin capture assay, which was performed with purified NOSs in 96-well plate...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZW1PZGUS Patent
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50014711(CHEMBL3262020 | US10759791, Compound 5S | US995101...)copy SMILEScopy InChI
Affinity DataKi:  3.28E+5nMAssay Description:Inhibition of purified bovine eNOS assessed as inhibition of nitric oxide-mediated oxidation of hemoglobin-A by hemoglobin capture assayMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Astex

LigandPNGBDBM50014711(CHEMBL3262020 | US10759791, Compound 5S | US995101...)copy SMILEScopy InChI
Affinity DataKi:  3.28E+5nMAssay Description:The NOSs isoform assays involved subjecting 3-8 to an oxyhemoglobin NO capture assay using a Biotek Gen5™ microplate reader. IC50 values for each com...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50014711(CHEMBL3262020 | US10759791, Compound 5S | US995101...)copy SMILEScopy InChI
Affinity DataKi:  3.28E+5nMAssay Description:Enzyme inhibition was evaluated by measuring NO production with the hemoglobin capture assay, which was performed with purified NOSs in 96-well plate...More data for this Ligand-Target Pair