Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
NMMLSC

Curated by PubChem BioAssay
LigandPNGBDBM32300(4-(2-methyl-3-imidazo[1,2-a]pyrimidinyl)-N-phenyl-...)copy SMILEScopy InChI
Affinity DataEC50:  1.01E+4nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935WVPCBioAssay
TargetBcl-2-related protein A1(Homo sapiens (Human))
NMMLSC

Curated by PubChem BioAssay
LigandPNGBDBM32300(4-(2-methyl-3-imidazo[1,2-a]pyrimidinyl)-N-phenyl-...)copy SMILEScopy InChI
Affinity DataEC50:  1.17E+4nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN728NPCBioAssay
LigandPNGBDBM32300(4-(2-methyl-3-imidazo[1,2-a]pyrimidinyl)-N-phenyl-...)copy SMILEScopy InChI
Affinity DataEC50:  8.97E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2697202PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
NMMLSC

Curated by PubChem BioAssay
LigandPNGBDBM32300(4-(2-methyl-3-imidazo[1,2-a]pyrimidinyl)-N-phenyl-...)copy SMILEScopy InChI
Affinity DataEC50:  8.71E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8QM3PCBioAssay
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
NMMLSC

Curated by PubChem BioAssay
LigandPNGBDBM32300(4-(2-methyl-3-imidazo[1,2-a]pyrimidinyl)-N-phenyl-...)copy SMILEScopy InChI
Affinity DataEC50:  8.93E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27SQ0PCBioAssay
TargetBcl-2-like protein 10 [11-204](Homo sapiens (Human))
NMMLSC

Curated by PubChem BioAssay
LigandPNGBDBM32300(4-(2-methyl-3-imidazo[1,2-a]pyrimidinyl)-N-phenyl-...)copy SMILEScopy InChI
Affinity DataEC50:  1.38E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GH9GBTPCBioAssay