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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Isoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)
(Homo sapiens (Human))
NMMLSC
Curated by
PubChem BioAssay
Ligand
BDBM32300
(4-(2-methyl-3-imidazo[1,2-a]pyrimidinyl)-N-phenyl-...)
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Affinity Data
EC50: 1.01E+4nM
pH: 7.4 T: 2°C
Assay Description:
The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
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In Depth
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BindingDB Entry DOI:
10.7270/Q2K935WV
PCBioAssay
Target
Bcl-2-related protein A1
(Homo sapiens (Human))
NMMLSC
Curated by
PubChem BioAssay
Ligand
BDBM32300
(4-(2-methyl-3-imidazo[1,2-a]pyrimidinyl)-N-phenyl-...)
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copy InChI
Affinity Data
EC50: 1.17E+4nM
pH: 7.4 T: 2°C
Assay Description:
The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
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In Depth
Details
BindingDB Entry DOI:
10.7270/Q2CN728N
PCBioAssay
Target
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human))
NMMLSC
Curated by
PubChem BioAssay
Ligand
BDBM32300
(4-(2-methyl-3-imidazo[1,2-a]pyrimidinyl)-N-phenyl-...)
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copy InChI
Affinity Data
EC50: 8.97E+3nM
Assay Description:
University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2697202
PCBioAssay
Target
Bcl-2-like protein 2
(Homo sapiens (Human))
NMMLSC
Curated by
PubChem BioAssay
Ligand
BDBM32300
(4-(2-methyl-3-imidazo[1,2-a]pyrimidinyl)-N-phenyl-...)
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copy InChI
Affinity Data
EC50: 8.71E+3nM
Assay Description:
University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2BR8QM3
PCBioAssay
Target
Apoptosis regulator Bcl-2
(Homo sapiens (Human))
NMMLSC
Curated by
PubChem BioAssay
Ligand
BDBM32300
(4-(2-methyl-3-imidazo[1,2-a]pyrimidinyl)-N-phenyl-...)
copy SMILES
copy InChI
Affinity Data
EC50: 8.93E+3nM
Assay Description:
University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2B27SQ0
PCBioAssay
Target
Bcl-2-like protein 10 [11-204]
(Homo sapiens (Human))
NMMLSC
Curated by
PubChem BioAssay
Ligand
BDBM32300
(4-(2-methyl-3-imidazo[1,2-a]pyrimidinyl)-N-phenyl-...)
copy SMILES
copy InChI
Affinity Data
EC50: 1.38E+3nM
Assay Description:
University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2GH9GBT
PCBioAssay