Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Kalypsys, Inc

Curated by ChEMBL
LigandPNGBDBM50348734(CHEMBL1801473)copy SMILEScopy InChI
Affinity DataEC50:  3.70E+3nMAssay Description:Inhibition of human iNOS expressed in HEK293 cells assessed as inhibition of nitric oxide production after 18 hrs using 2,3-diaminonaphthalene by flu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z9584PubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Kalypsys, Inc

Curated by ChEMBL
LigandPNGBDBM50348734(CHEMBL1801473)copy SMILEScopy InChI
Affinity DataEC50:  1.50E+4nMAssay Description:Inhibition of human eNOS expressed in HEK293 cells assessed as inhibition A23187 induced nitric oxide production incubated for 24 hrs measured after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z9584PubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Kalypsys, Inc

Curated by ChEMBL
LigandPNGBDBM50348734(CHEMBL1801473)copy SMILEScopy InChI
Affinity DataEC50:  4.30E+3nMAssay Description:Inhibition of human nNOS expressed in HEK293 cells assessed as inhibition ionomycin induced nitric oxide production incubated for 24 hrs measured aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29Z9584PubMed