Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Kalypsys Inc.

LigandBDBM29243(quinolinone, 14)copy SMILEScopy InChI

Affinity DataEC50:  1.50E+4nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D798RBPubMed

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Kalypsys Inc.

LigandBDBM29243(quinolinone, 14)copy SMILEScopy InChI

Affinity DataEC50:  62nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D798RBPubMed