Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Kalypsys Inc.

LigandPNGBDBM29253(quinolinone, 24)copy SMILEScopy InChI
Affinity DataEC50:  16nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D798RBPubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Kalypsys Inc.

LigandPNGBDBM29253(quinolinone, 24)copy SMILEScopy InChI
Affinity DataEC50:  500nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D798RBPubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Kalypsys Inc.

LigandPNGBDBM29253(quinolinone, 24)copy SMILEScopy InChI
Affinity DataEC50:  6.80E+3nMT: 2°CAssay Description:HEK293 cells (ATCC) were transiently transfected with recombinant NOS and grown. Cells were trypsinized, resuspended to 5 00,000 cells/mL, and plated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D798RBPubMed