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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Mitogen-activated protein kinase 6
(Homo sapiens (Human))
TBA
Ligand
BDBM383383
(4-(9-((4-chloro-1H-pyrazol-1- yl)methyl)-8,9-dihyd...)
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copy InChI
Affinity Data
IC50: 0.0200nM
Assay Description:
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2KP85BC
US Patent
Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Saarland University
Ligand
BDBM383383
(4-(9-((4-chloro-1H-pyrazol-1- yl)methyl)-8,9-dihyd...)
copy SMILES
copy InChI
Affinity Data
IC50: 0.0200nM
Assay Description:
Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
BindingDB Entry DOI:
10.7270/Q23X88ZR
US Patent