Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
AbbVie Inc.

Curated by ChEMBL
LigandPNGBDBM309129((3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(trifluor...)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of [3H]N-Methyl-SSR504734 binding to human recombinant GlyT1c expressed in CHO cell membranes incubated for 1 hr by liquid scintillation s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CC137KPubMed
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG

US Patent
LigandPNGBDBM309129((3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(trifluor...)copy SMILEScopy InChI
Affinity DataKi: <10nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z60R48US Patent
TargetAlpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG

US Patent
LigandPNGBDBM309129((3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(trifluor...)copy SMILEScopy InChI
Affinity DataKi: <10nMAssay Description:Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z60R48US Patent