Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMitogen-activated protein kinase 6(Homo sapiens (Human))TBA

LigandBDBM365180(4-(9-((5-fluoropyridin-3- yl)oxy)-8,9-dihydro-7H-6...)copy SMILEScopy InChI

Affinity DataIC50: 25.8nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KP85BCUS Patent

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Amgen

LigandBDBM365180(4-(9-((5-fluoropyridin-3- yl)oxy)-8,9-dihydro-7H-6...)copy SMILEScopy InChI

Affinity DataIC50: 25.8nMAssay Description:Compounds were tested in an enzymatic assay using human ERK-2 (Mitogen Activated Kinase 1), recombinantly expressed as an n-terminal 6-His fusion pro...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9MJ5US Patent