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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
13
hits in this display
Target
Metabotropic glutamate receptor 3
(Homo sapiens (Human))
Janssen Research and Development
Curated by
ChEMBL
Ligand
BDBM50064444
(CHEMBL3401195)
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Affinity Data
IC50: 290nM
Assay Description:
Negative allosteric modulation at mGluR3 (unknown origin)
More data for this Ligand-Target Pair
Target Info
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UniProtKB/SwissProt
antibodypedia
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Ligand Info
CHEMBL
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PC sid
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In Depth
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Article
BindingDB Entry DOI:
10.7270/Q2057HNQ
PubMed
Target
Cytochrome P450 2C9
(Homo sapiens (Human))
Janssen Research and Development
Curated by
ChEMBL
Ligand
BDBM50064444
(CHEMBL3401195)
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Affinity Data
IC50: 2.00E+4nM
Assay Description:
Inhibition of human CYP2C9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2057HNQ
PubMed
Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Janssen Research and Development
Curated by
ChEMBL
Ligand
BDBM50064444
(CHEMBL3401195)
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Affinity Data
IC50: 2.00E+4nM
Assay Description:
Inhibition of human CYP1A2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2057HNQ
PubMed
Target
Cytochrome P450 3A4
(Homo sapiens (Human))
Janssen Research and Development
Curated by
ChEMBL
Ligand
BDBM50064444
(CHEMBL3401195)
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copy InChI
Affinity Data
IC50: 2.00E+4nM
Assay Description:
Inhibition of human CYP3A4
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2057HNQ
PubMed
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Janssen Research and Development
Curated by
ChEMBL
Ligand
BDBM50064444
(CHEMBL3401195)
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copy InChI
Affinity Data
IC50: 2.00E+4nM
Assay Description:
Inhibition of human CYP2D6
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2057HNQ
PubMed
Target
Metabotropic glutamate receptor 7
(Homo sapiens (Human))
Janssen Research and Development
Curated by
ChEMBL
Ligand
BDBM50064444
(CHEMBL3401195)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Positive allosteric modulation at mGluR7 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2057HNQ
PubMed
Target
Metabotropic glutamate receptor 8
(Homo sapiens (Human))
Janssen Research and Development
Curated by
ChEMBL
Ligand
BDBM50064444
(CHEMBL3401195)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Positive allosteric modulation at mGluR8 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2057HNQ
PubMed
Target
Metabotropic glutamate receptor 6
(Homo sapiens (Human))
Janssen Research and Development
Curated by
ChEMBL
Ligand
BDBM50064444
(CHEMBL3401195)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Positive allosteric modulation at mGluR6 (unknown origin)
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2057HNQ
PubMed
Target
Metabotropic glutamate receptor 4
(Homo sapiens (Human))
Janssen Research and Development
Curated by
ChEMBL
Ligand
BDBM50064444
(CHEMBL3401195)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Positive allosteric modulation at mGluR4 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2057HNQ
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Janssen Research and Development
Curated by
ChEMBL
Ligand
BDBM50064444
(CHEMBL3401195)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Positive allosteric modulation at mGluR2 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2057HNQ
PubMed
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Janssen Research and Development
Curated by
ChEMBL
Ligand
BDBM50064444
(CHEMBL3401195)
copy SMILES
copy InChI
Affinity Data
EC50: 86nM
Assay Description:
Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2057HNQ
PubMed
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Janssen Research and Development
Curated by
ChEMBL
Ligand
BDBM50064444
(CHEMBL3401195)
copy SMILES
copy InChI
Affinity Data
EC50: 85nM
Assay Description:
Positive allosteric modulation at rat mGluR5 expressed in HEK293 cells by calcium mobilization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2057HNQ
PubMed
Target
Metabotropic glutamate receptor 1
(Homo sapiens (Human))
Janssen Research and Development
Curated by
ChEMBL
Ligand
BDBM50064444
(CHEMBL3401195)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Positive allosteric modulation at mGluR1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2057HNQ
PubMed