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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Metabotropic glutamate receptor 4
(Rattus norvegicus (Rat))
Universit£ di Perugia
Curated by
ChEMBL
Ligand
BDBM50175072
((S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acet...)
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Affinity Data
Ki: 7.40E+3nM
Assay Description:
Displacement of [3H]L-AP4 from rat mGluR4 expressed in BHK cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2DZ0932
PubMed
Target
Metabotropic glutamate receptor 8
(Rattus norvegicus (Rat))
Universit£ di Perugia
Curated by
ChEMBL
Ligand
BDBM50175072
((S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acet...)
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Affinity Data
Ki: 6.30E+4nM
Assay Description:
Displacement of [3H]LY341495 from rat mGluR8 expressed in BHK cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2DZ0932
PubMed
Target
Metabotropic glutamate receptor 1
(RAT)
Universit£ di Perugia
Curated by
ChEMBL
Ligand
BDBM50175072
((S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acet...)
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copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at rat mGluR1 by measuring intracellular calcium concentration in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2DZ0932
PubMed
Target
Metabotropic glutamate receptor 7
(Homo sapiens (Human))
Universit£ di Perugia
Curated by
ChEMBL
Ligand
BDBM50175072
((S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acet...)
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copy InChI
Affinity Data
EC50: 7.00E+5nM
Assay Description:
Activity at human mGluR7 by measuring cAMP formation in BHK cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2DZ0932
PubMed
Target
Metabotropic glutamate receptor 4
(Rattus norvegicus (Rat))
Universit£ di Perugia
Curated by
ChEMBL
Ligand
BDBM50175072
((S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acet...)
copy SMILES
copy InChI
Affinity Data
EC50: 9.40E+3nM
Assay Description:
Functional activity at rat mGluR4
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2DZ0932
PubMed
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Universit£ di Perugia
Curated by
ChEMBL
Ligand
BDBM50175072
((S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acet...)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at rat mGluR5 by measuring intracellular calcium concentration in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2DZ0932
PubMed
Target
Metabotropic glutamate receptor 6
(Rattus norvegicus (Rat))
Universit£ di Perugia
Curated by
ChEMBL
Ligand
BDBM50175072
((S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acet...)
copy SMILES
copy InChI
Affinity Data
EC50: 1.30E+4nM
Assay Description:
Activity at rat mGluR6 by measuring cAMP formation in CHO cells
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2DZ0932
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
Universit£ di Perugia
Curated by
ChEMBL
Ligand
BDBM50175072
((S)-2-amino-2-((1R,2S)-2-phosphonocyclopropyl)acet...)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at human mGluR2 from BHK cells in [35S]GTP-gamma-S stimulation assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2DZ0932
PubMed