Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50434129(CHEMBL2381647)copy SMILEScopy InChI
Affinity DataKi:  284nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu3 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95CM9PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50434129(CHEMBL2381647)copy SMILEScopy InChI
Affinity DataKi:  4.41E+3nMAssay Description:Displacement of [3H]-LY459477 from recombinant human mGlu2 receptor expressed in HEK cell membranes after 90 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95CM9PubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50434129(CHEMBL2381647)copy SMILEScopy InChI
Affinity DataEC50:  9.37E+3nMAssay Description:Agonist activity at human mGlu6 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003G4PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50434129(CHEMBL2381647)copy SMILEScopy InChI
Affinity DataEC50:  21nMAssay Description:Displacement of [3H]-pCCK-8 from cholecystokinin-A receptor in guinea pig pancreatic membraneMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95CM9PubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50434129(CHEMBL2381647)copy SMILEScopy InChI
Affinity DataEC50:  25nMAssay Description:Agonist activity at human mGlu3 receptor expressed in HEK cells assessed as inhibition of forskolin-stimulated cAMP formation after 20 mins by HTRF a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95CM9PubMed
TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50434129(CHEMBL2381647)copy SMILEScopy InChI
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at human mGlu8 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003G4PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50434129(CHEMBL2381647)copy SMILEScopy InChI
Affinity DataEC50:  21nMAssay Description:Agonist activity at human mGlu2 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003G4PubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50434129(CHEMBL2381647)copy SMILEScopy InChI
Affinity DataEC50:  25nMAssay Description:Agonist activity at human mGlu3 receptor expressed in golden Syrian hamster AV12 cells coexpressing EAAT1 after 20 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20003G4PubMed