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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
University of Cincinnati
Curated by
ChEMBL
Ligand
BDBM50131256
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
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Affinity Data
Ki: 64nM
Assay Description:
Binding affinity towards human Melanocortin 1 receptor (hMC1R)
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
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In Depth
Details
BindingDB Entry DOI:
10.7270/Q2474BD9
PubMed
Target
Melanocortin receptor 4
(Homo sapiens (Human))
University of Cincinnati
Curated by
ChEMBL
Ligand
BDBM50131256
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
copy SMILES
copy InChI
Affinity Data
Ki: 170nM
Assay Description:
In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2474BD9
PubMed
Target
Melanocortin receptor 3
(Homo sapiens (Human))
University of Cincinnati
Curated by
ChEMBL
Ligand
BDBM50131256
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
copy SMILES
copy InChI
Affinity Data
Ki: 540nM
Assay Description:
Binding affinity towards human Melanocortin 3 receptor (hMC3R)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2474BD9
PubMed
Target
Melanocortin receptor 3
(Homo sapiens (Human))
University of Cincinnati
Curated by
ChEMBL
Ligand
BDBM50131256
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
copy SMILES
copy InChI
Affinity Data
EC50: 120nM
Assay Description:
In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2474BD9
PubMed
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
University of Cincinnati
Curated by
ChEMBL
Ligand
BDBM50131256
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
copy SMILES
copy InChI
Affinity Data
EC50: 6.5nM
Assay Description:
In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2474BD9
PubMed
Target
Melanocortin receptor 4
(Homo sapiens (Human))
University of Cincinnati
Curated by
ChEMBL
Ligand
BDBM50131256
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
copy SMILES
copy InChI
Affinity Data
EC50: 23nM
Assay Description:
In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC4R)
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2474BD9
PubMed