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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Nitric oxide synthase, brain
(Homo sapiens (Human))
NeurAxon, Inc.
US Patent
Ligand
BDBM106749
(CHEMBL1823378 | US8586620, 184)
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copy InChI
Affinity Data
IC50: 1.00E+3nM
Assay Description:
Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2348J0K
US Patent
Target
Nitric oxide synthase, brain
(Homo sapiens (Human))
NeurAxon, Inc.
US Patent
Ligand
BDBM106749
(CHEMBL1823378 | US8586620, 184)
copy SMILES
copy InChI
Affinity Data
IC50: 1.00E+3nM
Assay Description:
Inhibition of recombinant human nNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine into [3H]-L-citrull...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2JD4X63
PubMed
Target
Nitric oxide synthase, endothelial
(Homo sapiens (Human))
NeurAxon, Inc.
US Patent
Ligand
BDBM106749
(CHEMBL1823378 | US8586620, 184)
copy SMILES
copy InChI
Affinity Data
IC50: 1.90E+4nM
Assay Description:
Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2348J0K
US Patent
Target
Nitric oxide synthase, endothelial
(Homo sapiens (Human))
NeurAxon, Inc.
US Patent
Ligand
BDBM106749
(CHEMBL1823378 | US8586620, 184)
copy SMILES
copy InChI
Affinity Data
IC50: 1.91E+4nM
Assay Description:
Inhibition of recombinant human eNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine into [3H]-L-citrull...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2JD4X63
PubMed
Target
Nitric oxide synthase, inducible
(Homo sapiens (Human))
NeurAxon Inc.
Curated by
ChEMBL
Ligand
BDBM106749
(CHEMBL1823378 | US8586620, 184)
copy SMILES
copy InChI
Affinity Data
IC50: 1.00E+5nM
Assay Description:
Inhibition of recombinant human iNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine into [3H]-L-citrull...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2JD4X63
PubMed