Home
About
Info
Download
WebServices
Contact
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
54
hits in this display
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: 89nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q25D8QCZ
PubMed
Target
Metabotropic glutamate receptor 1
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.20E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2J67FGZ
PubMed
Target
Glutamate receptor ionotropic, kainate 3
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.74E+3nM
Assay Description:
Displacement of [3H[SYM2081 from rat recombinant GluK3a expressed in sS9 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q20Z73HW
PubMed
Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.90E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2J67FGZ
PubMed
Target
Glutamate metabotropic receptor 5
(PORCINE)
CNRS CCIPE
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.93E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2WM1BXH
PubMed
Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: 2.00E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2M043ZH
PubMed
Target
Glutamate receptor ionotropic, kainate 1
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
Ki: 2.43E+3nM
Assay Description:
Displacement of [3H[SYM2081 from rat recombinant GluK1(Q)1b expressed in sS9 cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q20Z73HW
PubMed
Target
Glutamate metabotropic receptor 5
(PORCINE)
CNRS CCIPE
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: 2.87E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2WM1BXH
PubMed
Target
Glutamate receptor ionotropic, kainate 2
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
Ki: 3.23E+3nM
Assay Description:
Displacement of [3H[SYM2081 from rat recombinant GluK2(VCR)a expressed in sS9 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q20Z73HW
PubMed
Target
Metabotropic glutamate receptor 1
(RAT)
The Royal Danish School of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2FT8JK6
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2FT8JK6
PubMed
Target
Glutamate metabotropic receptor 1
(PORCINE)
CNRS CCIPE
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2WM1BXH
PubMed
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
The Royal Danish School of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2FT8JK6
PubMed
Target
Metabotropic glutamate receptor 4
(Rattus norvegicus (Rat))
The Royal Danish School of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2FT8JK6
PubMed
Target
Metabotropic glutamate receptor 4
(Homo sapiens (Human))
Emory University
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2M043ZH
PubMed
Target
Metabotropic glutamate receptor 3
(Homo sapiens (Human))
Emory University
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2M043ZH
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2M043ZH
PubMed
Target
Metabotropic glutamate receptor 1
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2M043ZH
PubMed
Target
Metabotropic glutamate receptor 6
(Homo sapiens (Human))
Emory University
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2M043ZH
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2M61HS5
PubMed
Target
Metabotropic glutamate receptor 4
(Rattus norvegicus (Rat))
The Royal Danish School of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2M61HS5
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2MP51T5
PubMed
Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.70E+4nM
Assay Description:
Agonist potency against cloned metabotropic glutamate receptor 5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2DZ090Q
PubMed
Target
Metabotropic glutamate receptor 1
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: 4.30E+4nM
Assay Description:
Agonist potency against cloned human metabotropic glutamate receptor 1
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2DZ090Q
PubMed
Target
Glutamate receptor 2
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Displacement of [3H[AMPA from rat recombinant GluA2(R)o expressed in sS9 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q20Z73HW
PubMed
Target
Glutamate receptor 1
(Rattus norvegicus (Rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Displacement of [3H[AMPA from rat recombinant GluA1o expressed in sS9 cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q20Z73HW
PubMed
Target
Glutamate receptor 4
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Displacement of [3H[AMPA from rat recombinant GluA4o expressed in sS9 cells
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q20Z73HW
PubMed
Target
Glutamate receptor 3
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+5nM
Assay Description:
Displacement of [3H[AMPA from rat recombinant GluA3o expressed in sS9 cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q20Z73HW
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.10E+5nM
Assay Description:
Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2).
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2DZ090Q
PubMed
Target
Metabotropic glutamate receptor 4
(Homo sapiens (Human))
Emory University
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+6nM
Assay Description:
Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2DZ090Q
PubMed
Target
Glutamate receptor 2
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at rat cloned iGluR2 expressed in human HEK293 cells by calcium imaging assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2Z320HT
PubMed
Target
Glutamate receptor 1
(Rattus norvegicus (Rat))
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at rat cloned iGluR1 expressed in human HEK293 cells by calcium imaging assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2Z320HT
PubMed
Target
Glutamate receptor ionotropic, kainate 1
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at rat cloned iGluR5 expressed in human HEK293 cells by calcium imaging assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2Z320HT
PubMed
Target
Glutamate receptor 4
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at rat cloned iGluR4 expressed in human HEK293 cells by calcium imaging assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2Z320HT
PubMed
Target
Glutamate receptor 3
(RAT)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at rat cloned iGluR3 expressed in human HEK293 cells by calcium imaging assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2Z320HT
PubMed
Target
Metabotropic glutamate receptor 4
(Rattus norvegicus (Rat))
The Royal Danish School of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at rat cloned mGluR4 expressed in CHO cells assessed as effect on cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2Z320HT
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.
Curated by
PDSP K
i
Database
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: 1.10E+5nM
Assay Description:
Activity at rat cloned mGluR2 expressed in CHO cells assessed as effect on cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2Z320HT
PubMed
Target
Metabotropic glutamate receptor 1
(RAT)
The Royal Danish School of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: 4.30E+4nM
Assay Description:
Activity at rat cloned mGluR1a expressed in CHO cells assessed as effect on cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2Z320HT
PubMed
Target
Metabotropic glutamate receptor 3
(Rattus norvegicus (Rat))
CNS Research
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: 1.00E+4nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR3 in rat
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q20R9Q1R
PubMed
Target
Metabotropic glutamate receptor 6
(Rattus norvegicus (Rat))
CNS Research
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: 1.00E+6nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR6 in rat
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q20R9Q1R
PubMed
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
The Royal Danish School of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: 1.00E+4nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR5a in rat
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q20R9Q1R
PubMed
Target
Metabotropic glutamate receptor 4
(Rattus norvegicus (Rat))
The Royal Danish School of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: 5.90E+5nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR4a in rat
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q20R9Q1R
PubMed
Target
Metabotropic glutamate receptor 1
(RAT)
The Royal Danish School of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: 6.00E+4nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR1c in rat
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q20R9Q1R
PubMed
Target
Metabotropic glutamate receptor 8
(Mus musculus)
CNS Research
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+5nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR8 in mouse
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q20R9Q1R
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.
Curated by
PDSP K
i
Database
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: 3.50E+4nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR2 in rat
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q20R9Q1R
PubMed
Target
Glutamate receptor ionotropic, kainate 2
(Rattus norvegicus)
TBA
Curated by
ChEMBL
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Activity at rat cloned iGluR6 expressed in human HEK293 cells by calcium imaging assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2Z320HT
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
EC50: 1.10E+5nM
Assay Description:
Compound was evaluated for agonistic activity against mGluR2 alpha metabotropic receptor subtype in rat cortical slice model
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q27P8XJ2
PubMed
Target
Metabotropic glutamate receptor 1
(RAT)
The Royal Danish School of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
EC50: 4.30E+4nM
Assay Description:
Compound was evaluated for agonistic activity against mGluR1 alpha metabotropic receptor subtype in rat cortical slice model
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q27P8XJ2
PubMed
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
The Royal Danish School of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: 1.00E+4nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR5a in rat
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q20R9Q1R
PubMed
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
The Royal Danish School of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: 8.00E+3nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR5b in rat
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q20R9Q1R
PubMed
Target
Metabotropic glutamate receptor 1
(RAT)
The Royal Danish School of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: 6.00E+3nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR1a in rat
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q20R9Q1R
PubMed
Target
Metabotropic glutamate receptor 1
(RAT)
The Royal Danish School of Pharmacy
Curated by
PDSP K
i
Database
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: 4.40E+4nM
Assay Description:
Concentration for half maximal activation of metabotropic glutamate mGluR1b in rat
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q20R9Q1R
PubMed
Target
Metabotropic glutamate receptor 1
(Homo sapiens (Human))
F. Hoffmann-La Roche
Curated by
PDSP K
i
Database
Ligand
BDBM50034501
((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)
copy SMILES
copy InChI
Affinity Data
EC50: 6.00E+3nM
Assay Description:
Effective concentration of the compound for half maximal stimulation of PI hydrolysis (mGluR1a)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2765DFJ
PubMed
Target
Metabotropic glutamate receptor 4
(Homo sapiens (Human))
Emory University
Curated by
PDSP K
i
Database
Ligand
BDBM82355
(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)
copy SMILES
copy InChI
Affinity Data
EC50: >1.00E+6nM
Assay Description:
Compound was evaluated for agonistic activity against mGluR4a alpha metabotropic receptor subtype in rat cortical slice model
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q27P8XJ2
PubMed
Displayed 1 to 50 (of 54 total ) |
Next
|
Last
>>