Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 54 hits in this display   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi:  89nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8QCZPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67FGZPubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataKi:  1.74E+3nMAssay Description:Displacement of [3H[SYM2081 from rat recombinant GluK3a expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73HWPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi:  1.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67FGZPubMed
TargetGlutamate metabotropic receptor 5(PORCINE)
CNRS CCIPE

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi:  1.93E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1BXHPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043ZHPubMed
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataKi:  2.43E+3nMAssay Description:Displacement of [3H[SYM2081 from rat recombinant GluK1(Q)1b expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73HWPubMed
TargetGlutamate metabotropic receptor 5(PORCINE)
CNRS CCIPE

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi:  2.87E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1BXHPubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataKi:  3.23E+3nMAssay Description:Displacement of [3H[SYM2081 from rat recombinant GluK2(VCR)a expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73HWPubMed
TargetMetabotropic glutamate receptor 1(RAT)
The Royal Danish School of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JK6PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JK6PubMed
TargetGlutamate metabotropic receptor 1(PORCINE)
CNRS CCIPE

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WM1BXHPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
The Royal Danish School of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JK6PubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
The Royal Danish School of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8JK6PubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043ZHPubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043ZHPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043ZHPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043ZHPubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043ZHPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61HS5PubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
The Royal Danish School of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61HS5PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP51T5PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi:  1.70E+4nMAssay Description:Agonist potency against cloned metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ090QPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi:  4.30E+4nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ090QPubMed
TargetGlutamate receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA2(R)o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73HWPubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA1o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73HWPubMed
TargetGlutamate receptor 4(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA4o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73HWPubMed
TargetGlutamate receptor 3(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H[AMPA from rat recombinant GluA3o expressed in sS9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z73HWPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ090QPubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+6nMAssay Description:Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ090QPubMed
TargetGlutamate receptor 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+6nMAssay Description:Activity at rat cloned iGluR2 expressed in human HEK293 cells by calcium imaging assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z320HTPubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+6nMAssay Description:Activity at rat cloned iGluR1 expressed in human HEK293 cells by calcium imaging assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z320HTPubMed
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+6nMAssay Description:Activity at rat cloned iGluR5 expressed in human HEK293 cells by calcium imaging assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z320HTPubMed
TargetGlutamate receptor 4(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+6nMAssay Description:Activity at rat cloned iGluR4 expressed in human HEK293 cells by calcium imaging assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z320HTPubMed
TargetGlutamate receptor 3(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+6nMAssay Description:Activity at rat cloned iGluR3 expressed in human HEK293 cells by calcium imaging assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z320HTPubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
The Royal Danish School of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+6nMAssay Description:Activity at rat cloned mGluR4 expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z320HTPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.

Curated by PDSP Ki Database
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50:  1.10E+5nMAssay Description:Activity at rat cloned mGluR2 expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z320HTPubMed
TargetMetabotropic glutamate receptor 1(RAT)
The Royal Danish School of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50:  4.30E+4nMAssay Description:Activity at rat cloned mGluR1a expressed in CHO cells assessed as effect on cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z320HTPubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
CNS Research

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR3 in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9Q1RPubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
CNS Research

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+6nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR6 in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9Q1RPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
The Royal Danish School of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5a in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9Q1RPubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
The Royal Danish School of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50:  5.90E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR4a in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9Q1RPubMed
TargetMetabotropic glutamate receptor 1(RAT)
The Royal Danish School of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50:  6.00E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1c in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9Q1RPubMed
TargetMetabotropic glutamate receptor 8(Mus musculus)
CNS Research

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR8 in mouseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9Q1RPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.

Curated by PDSP Ki Database
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50:  3.50E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR2 in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9Q1RPubMed
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+6nMAssay Description:Activity at rat cloned iGluR6 expressed in human HEK293 cells by calcium imaging assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z320HTPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
F. Hoffmann-La Roche Ltd.

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataEC50:  1.10E+5nMAssay Description:Compound was evaluated for agonistic activity against mGluR2 alpha metabotropic receptor subtype in rat cortical slice modelMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8XJ2PubMed
TargetMetabotropic glutamate receptor 1(RAT)
The Royal Danish School of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataEC50:  4.30E+4nMAssay Description:Compound was evaluated for agonistic activity against mGluR1 alpha metabotropic receptor subtype in rat cortical slice modelMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8XJ2PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
The Royal Danish School of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5a in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9Q1RPubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
The Royal Danish School of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50:  8.00E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR5b in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9Q1RPubMed
TargetMetabotropic glutamate receptor 1(RAT)
The Royal Danish School of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50:  6.00E+3nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1a in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9Q1RPubMed
TargetMetabotropic glutamate receptor 1(RAT)
The Royal Danish School of Pharmacy

Curated by PDSP Ki Database
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50:  4.40E+4nMAssay Description:Concentration for half maximal activation of metabotropic glutamate mGluR1b in ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9Q1RPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50034501((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...)copy SMILEScopy InChI
Affinity DataEC50:  6.00E+3nMAssay Description:Effective concentration of the compound for half maximal stimulation of PI hydrolysis (mGluR1a)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2765DFJPubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM82355(Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid(Iboten...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+6nMAssay Description:Compound was evaluated for agonistic activity against mGluR4a alpha metabotropic receptor subtype in rat cortical slice modelMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27P8XJ2PubMed
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