Home
About
Info
Download
WebServices
Contact
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
23
hits in this display
Target
Metabotropic glutamate receptor 8
(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
Ki: 210nM
Assay Description:
Agonist potency against cloned Metabotropic glutamate receptor 8 (mGluR-8).
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2DZ090Q
PubMed
Target
Metabotropic glutamate receptor 8
(Rattus norvegicus (Rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.30E+3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q27P8WZ1
PubMed
Target
Metabotropic glutamate receptor 6
(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
Ki: 4.70E+3nM
Assay Description:
Agonist potency against cloned Metabotropic glutamate receptor 6 (mGluR-6).
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2DZ090Q
PubMed
Target
Metabotropic glutamate receptor 4
(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
Ki: 5.20E+3nM
Assay Description:
Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2DZ090Q
PubMed
Target
Glutamate receptor 3
(RAT)
Eli Lilly and Company
Curated by
PDSP K
i
Database
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
Ki: >1.00E+4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2V986M2
PubMed
Target
Metabotropic glutamate receptor 7
(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.85E+5nM
Assay Description:
Agonist potency against cloned Metabotropic glutamate receptor 7 (mGluR-7).
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2DZ090Q
PubMed
Target
Metabotropic glutamate receptor 3
(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
Ki: >2.00E+5nM
Assay Description:
Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3).
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2DZ090Q
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
Ki: >3.00E+5nM
Assay Description:
Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2).
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2DZ090Q
PubMed
Target
Metabotropic glutamate receptor 5
(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
Ki: >5.00E+5nM
Assay Description:
Agonist potency against cloned metabotropic glutamate receptor 5
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2DZ090Q
PubMed
Target
Metabotropic glutamate receptor 1
(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
Ki: >5.00E+5nM
Assay Description:
Agonist potency against cloned human metabotropic glutamate receptor 1
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2DZ090Q
PubMed
Target
Metabotropic glutamate receptor 1
(RAT)
Lilly, SA
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
EC50: >5.00E+5nM
Assay Description:
Metabotropic glutamate receptor 1 agonist activity as basal [3H]- IP formation in rat
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2K936Z5
PubMed
Target
Metabotropic glutamate receptor 5
(Rattus norvegicus (Rat))
Lilly, SA
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
EC50: >5.00E+5nM
Assay Description:
Metabotropic glutamate receptor 5 agonist activity as basal [3H]- IP formation in rat
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2K936Z5
PubMed
Target
Metabotropic glutamate receptor 2
(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
EC50: >3.00E+5nM
Assay Description:
Metabotropic glutamate receptor 2 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2K936Z5
PubMed
Target
Metabotropic glutamate receptor 6
(Rattus norvegicus (Rat))
Lilly, SA
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
EC50: 4.70E+3nM
Assay Description:
Metabotropic glutamate receptor 6 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cells
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2K936Z5
PubMed
Target
Metabotropic glutamate receptor 4
(Rattus norvegicus (Rat))
Lilly, SA
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
EC50: 5.20E+3nM
Assay Description:
Metabotropic glutamate receptor 4 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2K936Z5
PubMed
Target
Metabotropic glutamate receptor 4
(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
EC50: 4.70E+3nM
Assay Description:
Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2VT1R95
PubMed
Target
Metabotropic glutamate receptor 4
(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
EC50: 5.20E+3nM
Assay Description:
Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR7b
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q26972SC
PubMed
Target
Metabotropic glutamate receptor 7
(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
EC50: 4.80E+4nM
Assay Description:
Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR4a
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q26972SC
PubMed
Target
Metabotropic glutamate receptor 7
(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
EC50: 4.80E+4nM
Assay Description:
Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR7b
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q26972SC
PubMed
Target
Metabotropic glutamate receptor 3
(Rattus norvegicus (Rat))
Lilly, SA
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
EC50: >2.00E+5nM
Assay Description:
Metabotropic glutamate receptor 3 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2K936Z5
PubMed
Target
Metabotropic glutamate receptor 4
(Homo sapiens (Human))
The Royal Danish School of Pharmacy
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
EC50: 3.20E+3nM
Assay Description:
Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR4a
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q26972SC
PubMed
Target
Metabotropic glutamate receptor 8
(Rattus norvegicus (Rat))
University of Toronto
Curated by
PDSP K
i
Database
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
EC50: 210nM
Assay Description:
Metabotropic glutamate receptor 8 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2K936Z5
PubMed
Target
Metabotropic glutamate receptor 7
(Rattus norvegicus (Rat))
Lilly, SA
Curated by
ChEMBL
Ligand
BDBM50004881
((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)
copy SMILES
copy InChI
Affinity Data
EC50: 1.85E+5nM
Assay Description:
Metabotropic glutamate receptor 7 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2K936Z5
PubMed