Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 23 hits in this display   

TargetMetabotropic glutamate receptor 8(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataKi:  210nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 8 (mGluR-8).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ090QPubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8WZ1PubMed
TargetMetabotropic glutamate receptor 6(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataKi:  4.70E+3nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 6 (mGluR-6).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ090QPubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataKi:  5.20E+3nMAssay Description:Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ090QPubMed
TargetGlutamate receptor 3(RAT)
Eli Lilly and Company

Curated by PDSP Ki Database
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V986M2PubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataKi:  1.85E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 7 (mGluR-7).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ090QPubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 3 (mGluR-3).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ090QPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataKi: >3.00E+5nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ090QPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+5nMAssay Description:Agonist potency against cloned metabotropic glutamate receptor 5More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ090QPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+5nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ090QPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+5nMAssay Description:Metabotropic glutamate receptor 1 agonist activity as basal [3H]- IP formation in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+5nMAssay Description:Metabotropic glutamate receptor 5 agonist activity as basal [3H]- IP formation in ratMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataEC50: >3.00E+5nMAssay Description:Metabotropic glutamate receptor 2 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 6(Rattus norvegicus (Rat))
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataEC50:  4.70E+3nMAssay Description:Metabotropic glutamate receptor 6 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataEC50:  5.20E+3nMAssay Description:Metabotropic glutamate receptor 4 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataEC50:  4.70E+3nMAssay Description:Agonistic activity at Metabotropic glutamate receptor 4 expressed in mammalian cells by GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VT1R95PubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataEC50:  5.20E+3nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR7bMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26972SCPubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataEC50:  4.80E+4nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR4aMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26972SCPubMed
TargetMetabotropic glutamate receptor 7(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataEC50:  4.80E+4nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR7bMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26972SCPubMed
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataEC50: >2.00E+5nMAssay Description:Metabotropic glutamate receptor 3 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataEC50:  3.20E+3nMAssay Description:Compound was evaluated for the inhibition of forskolin stimulated cAMP accumulation in CHO cells expressing hmGluR4aMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26972SCPubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataEC50:  210nMAssay Description:Metabotropic glutamate receptor 8 agonist activity against forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed
TargetMetabotropic glutamate receptor 7(Rattus norvegicus (Rat))
Lilly, SA

Curated by ChEMBL
LigandPNGBDBM50004881((RS) PPG | Amino-(4-phosphono-phenyl)-acetic acid ...)copy SMILEScopy InChI
Affinity DataEC50:  1.85E+5nMAssay Description:Metabotropic glutamate receptor 7 agonist activity to influence forskolin stimulated c-AMP formation in rat nonneuronal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K936Z5PubMed