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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Melanocortin receptor 3
(Homo sapiens (Human))
University of Arizona
Curated by
ChEMBL
Ligand
BDBM50230814
(CHEMBL253788 | c[CO-o-C6H4-CO-Pro-D-Nal(2)-Arg-Trp...)
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Affinity Data
IC50: 32nM
Assay Description:
Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC3 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2V125N2
PubMed
Target
Melanocortin receptor 5
(Homo sapiens (Human))
University of Arizona
Curated by
ChEMBL
Ligand
BDBM50230814
(CHEMBL253788 | c[CO-o-C6H4-CO-Pro-D-Nal(2)-Arg-Trp...)
copy SMILES
copy InChI
Affinity Data
IC50: 210nM
Assay Description:
Agonist activity at human MC5 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2V125N2
PubMed
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
University of Arizona
Curated by
ChEMBL
Ligand
BDBM50230814
(CHEMBL253788 | c[CO-o-C6H4-CO-Pro-D-Nal(2)-Arg-Trp...)
copy SMILES
copy InChI
Affinity Data
IC50: 410nM
Assay Description:
Agonist activity at human MC1 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2V125N2
PubMed
Target
Melanocortin receptor 4
(Homo sapiens (Human))
University of Arizona
Curated by
ChEMBL
Ligand
BDBM50230814
(CHEMBL253788 | c[CO-o-C6H4-CO-Pro-D-Nal(2)-Arg-Trp...)
copy SMILES
copy InChI
Affinity Data
IC50: 430nM
Assay Description:
Displacement of [125I][Nle4,D-Phe7]alpha-MSH from human MC4 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2V125N2
PubMed
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
University of Arizona
Curated by
ChEMBL
Ligand
BDBM50230814
(CHEMBL253788 | c[CO-o-C6H4-CO-Pro-D-Nal(2)-Arg-Trp...)
copy SMILES
copy InChI
Affinity Data
EC50: >5.00E+3nM
Assay Description:
Agonist activity at human MC1 receptor expressed in HEK293 cells assessed as intracellular cAMP accumulation
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2V125N2
PubMed