Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

LigandPNGBDBM21971(3-[(4S,6S)-4,8-diamino-6-hydroxyoctyl]-1-nitroguan...)copy SMILEScopy InChI
Affinity DataKi:  290nM ΔG°:  -37.9kJ/mole IC50: 2.40E+3nMpH: 7.4 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB72W1PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

LigandPNGBDBM21971(3-[(4S,6S)-4,8-diamino-6-hydroxyoctyl]-1-nitroguan...)copy SMILEScopy InChI
Affinity DataIC50: 2.57E+5nMpH: 7.4 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB72W1PubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

LigandPNGBDBM21971(3-[(4S,6S)-4,8-diamino-6-hydroxyoctyl]-1-nitroguan...)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+6nMpH: 7.4 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RB72W1PubMed