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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
9
hits in this display
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Neurocrine Biosciences, Inc.
Curated by
ChEMBL
Ligand
BDBM50155390
(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
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Affinity Data
Ki: 21nM
Assay Description:
Agonist activity at human MC4 receptor expressed in HEK293 cells assessed as stimulation of cAMP production
More data for this Ligand-Target Pair
Target Info
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antibodypedia
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Ligand Info
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In Depth
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Article
BindingDB Entry DOI:
10.7270/Q2610ZSQ
PubMed
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Neurocrine Biosciences, Inc.
Curated by
ChEMBL
Ligand
BDBM50155390
(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
copy SMILES
copy InChI
Affinity Data
Ki: 21nM
Assay Description:
Tested for inhibition of binding to MC4 receptor
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
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In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2DB82K8
PubMed
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Neurocrine Biosciences, Inc.
Curated by
ChEMBL
Ligand
BDBM50155390
(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
copy SMILES
copy InChI
Affinity Data
Ki: 21nM
Assay Description:
Binding affinity for melanocortin-4 receptor transfected in HEK 293 cells using [125I]-NDP-MSH as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q22Z1527
PubMed
Target
Melanocortin receptor 5
(Homo sapiens (Human))
Neurocrine Biosciences, Inc.
Curated by
ChEMBL
Ligand
BDBM50155390
(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.00E+3nM
Assay Description:
Binding affinity towards human melanocortin 5 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2DB82K8
PubMed
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Neurocrine Biosciences, Inc.
Curated by
ChEMBL
Ligand
BDBM50155390
(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.00E+3nM
Assay Description:
Binding affinity towards human melanocortin 3 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2DB82K8
PubMed
Target
Melanocortin receptor 5
(Homo sapiens (Human))
Neurocrine Biosciences, Inc.
Curated by
ChEMBL
Ligand
BDBM50155390
(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.00E+3nM
Assay Description:
Displacement of [125]NDP-MSH from human MC5 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2610ZSQ
PubMed
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Neurocrine Biosciences, Inc.
Curated by
ChEMBL
Ligand
BDBM50155390
(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.30E+3nM
Assay Description:
Binding affinity towards human melanocortin 1 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2DB82K8
PubMed
Target
Melanocyte-stimulating hormone receptor
(Homo sapiens (Human))
Neurocrine Biosciences, Inc.
Curated by
ChEMBL
Ligand
BDBM50155390
(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.30E+3nM
Assay Description:
Displacement of [125]NDP-MSH from human MC1 receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2610ZSQ
PubMed
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Neurocrine Biosciences, Inc.
Curated by
ChEMBL
Ligand
BDBM50155390
(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
copy SMILES
copy InChI
Affinity Data
Ki: 1.40E+3nM
Assay Description:
Displacement of [125]NDP-MSH from human MC3receptor expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2610ZSQ
PubMed