Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

LigandPNGBDBM21962(3-[(4S)-4-amino-5-[(2-aminoethyl)(hydroxy)amino]pe...)copy SMILEScopy InChI
Affinity DataKi:  120nM ΔG°:  -40.2kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

LigandPNGBDBM21962(3-[(4S)-4-amino-5-[(2-aminoethyl)(hydroxy)amino]pe...)copy SMILEScopy InChI
Affinity DataKi:  1.60E+4nM ΔG°:  -27.8kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W0947WPubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

LigandPNGBDBM21962(3-[(4S)-4-amino-5-[(2-aminoethyl)(hydroxy)amino]pe...)copy SMILEScopy InChI
Affinity DataKi:  7.30E+4nM ΔG°:  -24.0kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair