Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 21 hits in this display   

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50255304((S)-1-(4-amino-5-(2-aminoethylamino)pentyl)-3-nitr...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2V01PubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  120nMAssay Description:Inhibitory activity against Neuronal Nitric Oxide Synthase (nNOS)More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  120nMAssay Description:Inhibitory activity against recombinant rat nNOS.More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  150nM ΔG°:  -39.6kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  150nM ΔG°:  -39.6kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  170nM ΔG°:  -39.3kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  290nMAssay Description:Inhibitory activity against neuronal nitric oxide synthaseChecked by AuthorMore data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial [N368D](Bos taurus (bovine))
University of California at Irvine

LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  4.60E+3nM ΔG°:  -31.0kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+4nM ΔG°:  -27.5kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W0947WPubMed
TargetNitric oxide synthase, brain [D597N](Rattus norvegicus (rat))
University of California at Irvine

LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+4nM ΔG°:  -25.9kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  3.90E+4nMAssay Description:Inhibitory activity against Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3DQKPubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

LigandPNGBDBM50255304((S)-1-(4-amino-5-(2-aminoethylamino)pentyl)-3-nitr...)copy SMILEScopy InChI
Affinity DataKi:  3.90E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2V01PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  3.90E+4nMAssay Description:Inhibitory activity against recombinant murine iNOS.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29K4BX1PubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  7.30E+4nMAssay Description:Inhibitory activity against Inducible nitric oxide synthaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5TQVPubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University of California at Irvine

LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  8.00E+4nM ΔG°:  -23.8kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University of California at Irvine

LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  8.00E+4nM ΔG°:  -23.8kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University of California at Irvine

LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  1.91E+5nM ΔG°:  -21.6kJ/molepH: 7.5 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University of California at Irvine

LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  3.14E+5nMAssay Description:Inhibitory activity against recombinant bovine eNOS.More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University of California at Irvine

LigandPNGBDBM50255304((S)-1-(4-amino-5-(2-aminoethylamino)pentyl)-3-nitr...)copy SMILEScopy InChI
Affinity DataKi:  3.14E+5nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by hemoglobin capture assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2V01PubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
University of California at Irvine

LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  3.14E+5nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM21960(3-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-1-n...)copy SMILEScopy InChI
Affinity DataKi:  5.24E+5nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)Checked by AuthorMore data for this Ligand-Target Pair