Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33157(MLS000687602 | SMR000283375 | [2,3-bis(2-furanyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 6.46E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X8539PCBioAssay
TargetBcl-2-like protein 2(Homo sapiens (Human))
NMMLSC

Curated by PubChem BioAssay
LigandPNGBDBM33157(MLS000687602 | SMR000283375 | [2,3-bis(2-furanyl)-...)copy SMILEScopy InChI
Affinity DataEC50:  1.48E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BR8QM3PCBioAssay
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM33157(MLS000687602 | SMR000283375 | [2,3-bis(2-furanyl)-...)copy SMILEScopy InChI
Affinity DataEC50:  3.23E+4nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P55KXKPCBioAssay
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33157(MLS000687602 | SMR000283375 | [2,3-bis(2-furanyl)-...)copy SMILEScopy InChI
Affinity DataEC50:  4.55E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2697202PCBioAssay
TargetBcl-2-related protein A1(Homo sapiens (Human))
NMMLSC

Curated by PubChem BioAssay
LigandPNGBDBM33157(MLS000687602 | SMR000283375 | [2,3-bis(2-furanyl)-...)copy SMILEScopy InChI
Affinity DataEC50:  9.94E+3nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN728NPCBioAssay
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
NMMLSC

Curated by PubChem BioAssay
LigandPNGBDBM33157(MLS000687602 | SMR000283375 | [2,3-bis(2-furanyl)-...)copy SMILEScopy InChI
Affinity DataEC50:  1.60E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27SQ0PCBioAssay