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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Prostaglandin E2 receptor EP3 subtype
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50134526
(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
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Affinity Data
Ki: 3nM
Assay Description:
Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q26T0M1N
PubMed
Target
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50134526
(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
copy SMILES
copy InChI
Affinity Data
Ki: 120nM
Assay Description:
Ability to inhibit the binding of human DP receptor to PGD-2
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q26T0M1N
PubMed
Target
Prostaglandin E2 receptor EP4 subtype
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50134526
(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
copy SMILES
copy InChI
Affinity Data
Ki: 300nM
Assay Description:
Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q26T0M1N
PubMed
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50134526
(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
copy SMILES
copy InChI
Affinity Data
Ki: 400nM
Assay Description:
Ability of the compound to inhibit the binding of human human Tthromboxane A2 receptor to TXA2
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q26T0M1N
PubMed
Target
Prostacyclin receptor
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50134526
(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
copy SMILES
copy InChI
Affinity Data
Ki: 710nM
Assay Description:
Ability of the compound to inhibit the binding of human human IP receptor to Prostaglandin I2 receptor
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q26T0M1N
PubMed
Target
Prostaglandin E2 receptor EP2 subtype
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50134526
(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
copy SMILES
copy InChI
Affinity Data
Ki: 2.30E+3nM
Assay Description:
Affinity at human Prostanoid EP2 receptor in the human embryonic kidney (HEK) 293 cell line.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q26T0M1N
PubMed
Target
Prostaglandin F2-alpha receptor
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50134526
(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
copy SMILES
copy InChI
Affinity Data
Ki: 2.20E+4nM
Assay Description:
Ability of the compound to inhibit the binding of human human FP receptor to PGD-2
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q26T0M1N
PubMed
Target
Prostaglandin E2 receptor EP1 subtype
(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by
ChEMBL
Ligand
BDBM50134526
(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)
copy SMILES
copy InChI
Affinity Data
Ki: 4.80E+4nM
Assay Description:
Affinity at human Prostanoid EP1 receptor in the human embryonic kidney (HEK) 293 cell line.
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q26T0M1N
PubMed