Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50134526(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0M1NPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50134526(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)copy SMILEScopy InChI
Affinity DataKi:  120nMAssay Description:Ability to inhibit the binding of human DP receptor to PGD-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0M1NPubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50134526(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)copy SMILEScopy InChI
Affinity DataKi:  300nMAssay Description:Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0M1NPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50134526(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)copy SMILEScopy InChI
Affinity DataKi:  400nMAssay Description:Ability of the compound to inhibit the binding of human human Tthromboxane A2 receptor to TXA2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0M1NPubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50134526(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)copy SMILEScopy InChI
Affinity DataKi:  710nMAssay Description:Ability of the compound to inhibit the binding of human human IP receptor to Prostaglandin I2 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0M1NPubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50134526(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)copy SMILEScopy InChI
Affinity DataKi:  2.30E+3nMAssay Description:Affinity at human Prostanoid EP2 receptor in the human embryonic kidney (HEK) 293 cell line.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0M1NPubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50134526(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)copy SMILEScopy InChI
Affinity DataKi:  2.20E+4nMAssay Description:Ability of the compound to inhibit the binding of human human FP receptor to PGD-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0M1NPubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50134526(2-{2-[5-(2-Benzyloxy-phenyl)-thiophen-3-yl]-phenyl...)copy SMILEScopy InChI
Affinity DataKi:  4.80E+4nMAssay Description:Affinity at human Prostanoid EP1 receptor in the human embryonic kidney (HEK) 293 cell line.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0M1NPubMed