Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetThromboxane-A synthase(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50053768(5-[1-Phenyl-1-pyrazin-2-yl-meth-(Z)-ylideneaminoox...)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:TXA2 synthetase inhibition measured by the inhibition of TXB2 formation by human gel-filtered platelets incubated with [14C]-arachidonic acidMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP456GPubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50053768(5-[1-Phenyl-1-pyrazin-2-yl-meth-(Z)-ylideneaminoox...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMAssay Description:TXA2 receptor antagonism, measured by the displacement of [3H]SQ29,548 from the PGH-2/TXA-2 receptor on human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP456GPubMed