Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetCystine/glutamate transporter(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL

LigandBDBM50355002(CHEMBL1834954)copy SMILEScopy InChI

Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of xc-cystine-glutamate antiporter-mediated cystine uptake in human U87 cells using L-[14C]cystine as substrate after 15 mins by liquid sc...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5FCRPubMed

TargetCystine/glutamate transporter(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL

LigandBDBM50355002(CHEMBL1834954)copy SMILEScopy InChI

Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of xCT-mediated cystein/glutamate transporter (unknown origin) assessed as reduction in L-[14C]cyctein uptakeMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87F26PubMed