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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
Kyowa Hakko Kogyo Company, Ltd.
Curated by
ChEMBL
Ligand
BDBM50002750
(11-(2-Benzenesulfonylamino-ethylsulfanyl)-6,11-dih...)
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copy InChI
Affinity Data
Ki: 32nM
Assay Description:
Binding affinity at TXA2 receptor by measuring its ability to displace [3H]-U-46,619 from guinea pig platelets
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2NS0SV5
PubMed
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
Kyowa Hakko Kogyo Company, Ltd.
Curated by
ChEMBL
Ligand
BDBM50002750
(11-(2-Benzenesulfonylamino-ethylsulfanyl)-6,11-dih...)
copy SMILES
copy InChI
Affinity Data
Ki: 32nM
Assay Description:
Inhibition of the thromboxane A2 receptor assayed by binding to guinea pig platelets using [3H]-U-46,619 as radioligand
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2NS0SV5
PubMed
Target
Thromboxane A2 receptor
(Homo sapiens (Human))
Kyowa Hakko Kogyo Company, Ltd.
Curated by
ChEMBL
Ligand
BDBM50002750
(11-(2-Benzenesulfonylamino-ethylsulfanyl)-6,11-dih...)
copy SMILES
copy InChI
Affinity Data
Ki: 32nM
Assay Description:
Binding affinity at TXA2/PGH2 receptor by measuring its ability to displace [3H]-U-46,619 from guinea pig platelets
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2J38RG1
PubMed
Target
Thromboxane-A synthase
(Rattus norvegicus)
Kyowa Hakko Kogyo Company, Ltd.
Curated by
ChEMBL
Ligand
BDBM50002750
(11-(2-Benzenesulfonylamino-ethylsulfanyl)-6,11-dih...)
copy SMILES
copy InChI
Affinity Data
IC50: 2.40E+3nM
Assay Description:
Inhibitory effect of the compound against thromboxane A2 synthase binding to bovine platelets
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2NS0SV5
PubMed
Target
Thromboxane-A synthase
(Homo sapiens (Human))
Kyowa Hakko Kogyo Company, Ltd.
Curated by
ChEMBL
Ligand
BDBM50002750
(11-(2-Benzenesulfonylamino-ethylsulfanyl)-6,11-dih...)
copy SMILES
copy InChI
Affinity Data
IC50: 2.40E+4nM
Assay Description:
Compound was tested for its inhibitory activity against TXA2 synthase obtained from bovine platelet microsomes
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2NS0SV5
PubMed