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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Induced myeloid leukemia cell differentiation protein Mcl-1
(Homo sapiens (Human))
National Institute of Chemistry
Curated by
ChEMBL
Ligand
BDBM50016583
(2-(Phenylsulfonamido)benzoic Acid | 2-Benzenesulfo...)
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Affinity Data
Ki: 4.78E+4nM
Assay Description:
Inhibition of N-terminal His6-tagged human Mcl1 expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled Flu-Bid peptide based fluorescence ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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In Depth
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Article
BindingDB Entry DOI:
10.7270/Q2542RW2
PubMed
Target
Bcl-2-related protein A1
(Homo sapiens (Human))
National Institute of Chemistry
Curated by
ChEMBL
Ligand
BDBM50016583
(2-(Phenylsulfonamido)benzoic Acid | 2-Benzenesulfo...)
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Affinity Data
Ki: >1.00E+5nM
Assay Description:
Inhibition of N-terminal His6-tagged human Bfl-1 (1 to 151 residues), expressed in Escherichia coli Rosetta2 DE3 by fluorescent labeled FAM-Bid pepti...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2542RW2
PubMed
Target
Aldo-keto reductase family 1 member B1
(Rattus norvegicus)
Auburn University
Curated by
ChEMBL
Ligand
BDBM50016583
(2-(Phenylsulfonamido)benzoic Acid | 2-Benzenesulfo...)
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Affinity Data
IC50: 6.50E+4nM
Assay Description:
Inhibitory concentration against aldose reductase obtained from rat lens
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
BindingDB Entry DOI:
10.7270/Q2GM87WR
PubMed