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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
L-lactate dehydrogenase A chain
(Homo sapiens (Human))
Genentech
Curated by
ChEMBL
Ligand
BDBM50534330
(CHEMBL4520899)
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copy InChI
Affinity Data
IC50: 9nM
Assay Description:
Inhibition of human recombinant carboxy-terminal His-tagged LDHA by UV endpoint assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2V40ZP9
PubMed
Target
L-lactate dehydrogenase B chain
(Homo sapiens (Human))
Genentech
Curated by
ChEMBL
Ligand
BDBM50534330
(CHEMBL4520899)
copy SMILES
copy InChI
Affinity Data
IC50: 49nM
Assay Description:
Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2V40ZP9
PubMed
Target
L-lactate dehydrogenase A chain
(Homo sapiens (Human))
Genentech
Curated by
ChEMBL
Ligand
BDBM50534330
(CHEMBL4520899)
copy SMILES
copy InChI
Affinity Data
IC50: 670nM
Assay Description:
Inhibition of LDHA in human MiPaca2 cells assessed as inhibition of lactate production
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q2V40ZP9
PubMed