Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 68 hits in this display   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  600nM ΔG°:  -34.9kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W79PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coliChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09QFPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM50147625(CHEBI:16136 | SULFUR, PRECIPITATED)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibition of human CA1 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93BJFPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  600nM ΔG°:  -34.9kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W9583BPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  600nMpH: 8.3Assay Description:Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay at pH 8.3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930TGNPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28054D1PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  600nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 1 after 15 mins by CO2 hydrase assay at pH 7.5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN672RPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930VB8PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibitory constant against carbonic anhydrase IMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H995ZDPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibition of human carbonic anhydrase-1 by [18O]-exchange mass spectroscopyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ34GPPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X58JJPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD70TXPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibition of human recombinant wild type CA1 by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC846GPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T7KPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM50147625(CHEBI:16136 | SULFUR, PRECIPITATED)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95C24PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  600nMAssay Description:Inhibition of human carbonic anhydrase-1 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SV8PubMed
TargetCarbonic anhydrase, alpha family(Thiomicrospira crunogena (strain XCL-2))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of Thiomicrospira crunogena XCL-2 alpha-carbonic anhydrase expressed in Escherichia coli BL21 (DE3) cells by [18O]-exchange mass spectrosc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ34GPPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of human carbonic anhydrase-2 by [18O]-exchange mass spectroscopyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ34GPPubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IXMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X58JJPubMed
TargetCarbonic anhydrase 15 [19-324](Mus musculus (mouse))
Universita degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  9.20E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W79PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7DDZPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50147625(CHEBI:16136 | SULFUR, PRECIPITATED)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human CA2 incubated for 15 mins prior to testing by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K93BJFPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human carbonic anhydrase-2 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SV8PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human CA2 incubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028V0PPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 assessed as inhibition of CO2 hydration incubated for 15 mins prior to testing by stopped flow C...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD5012PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 assessed as inhibition of CO2 hydration preincubated for 15 mins by Lineweaver-burk plot methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M047FFPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930VB8PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human recombinant wild type CA2 by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC846GPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9QQQPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD70TXPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8806PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IIMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X58JJPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coliChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09QFPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibitory constant against carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H995ZDPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMpH: 8.3Assay Description:Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay at pH 8.3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930TGNPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMpH: 7.5Assay Description:Inhibition of human carbonic anhydrase 2 after 15 mins by CO2 hydrase assay at pH 7.5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN672RPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T7KPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50147625(CHEBI:16136 | SULFUR, PRECIPITATED)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95C24PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human carbonic anhydrase-2 by CO2 hydration reaction based colorimetric stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8FK8PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348N4MPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28054D1PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:Inhibition of human CA2 after 15 mins by stopped-flow/Co2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4ZJ0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nM ΔG°:  -24.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition of Helicobacter pylori alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W9583BPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+4nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W79PubMed
TargetCarbonic anhydrase(Methanosarcina thermophila)
Istituto di Biochimica delle Proteine - CNR

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1F27PubMed
TargetCarbonic anhydrase(Methanosarcina thermophila)
Istituto di Biochimica delle Proteine - CNR

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition of archaeon Methanosarcina thermophila gamma-CA after 15 mins by stopped-flow/Co2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4ZJ0PubMed
TargetCarbonic anhydrase(Methanosarcina thermophila)
Istituto di Biochimica delle Proteine - CNR

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+4nMAssay Description:Inhibitory constant against Zn-Cam (Methanosarcina thermophila)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H995ZDPubMed
TargetCarbonic anhydrase(Methanosarcina thermophila)
Istituto di Biochimica delle Proteine - CNR

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition of Methanosarcina thermophila recombinant carbonic anhydrase gamma assessed as inhibition of CO2 hydration preincubated for 15 mins by Lin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M047FFPubMed
TargetCarbonic anhydrase(Vibrio cholerae serotype O1 (strain ATCC 39315 / E...)
Universit£ degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  7.40E+4nM ΔG°:  -23.2kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition of Flaveria bidentis carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W9583BPubMed
TargetCarbonic anhydrase(Astrosclera willeyana)
Slovak Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  4.90E+5nMAssay Description:Inhibition of Astrosclera willeyana recombinant GST-tagged astrosclerin 3 expressed in Escherichia coli BL21-DE3-RIPL cells preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W66M7MPubMed
TargetCarbonic anhydrase(Stylophora pistillata)
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  5.80E+5nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T7KPubMed
TargetCarbonic anhydrase(Helicobacter pylori)
Università degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  5.80E+5nM ΔG°:  -18.5kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75F7KPubMed
TargetCarbonic anhydrase(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
University of Florida

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  6.20E+5nMpH: 8.3Assay Description:Inhibition of human carbonic anhydrase-2 by CO2 hydration reaction based colorimetric stopped-flow methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20V8FK8PubMed
TargetAlpha-carbonic anhydrase(Helicobacter pylori (strain G27))
Universit£ degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  6.90E+5nM ΔG°:  -17.7kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W9583BPubMed
TargetAlpha-carbonic anhydrase(Helicobacter pylori)
Università degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  6.90E+5nM ΔG°:  -18.0kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75F7KPubMed
TargetCarbonic anhydrase(Methanobacterium thermoautotrophicum)
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  7.00E+5nMAssay Description:Inhibitory constant against methanoarchaeon Methanobacterium thermoautotrophicum (Cab)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H995ZDPubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  7.10E+5nMAssay Description:Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T7KPubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  1.24E+6nMAssay Description:Inhibition of human recombinant CA7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29W0G8RPubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  3.90E+6nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IVMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X58JJPubMed
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  3.90E+6nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1W79PubMed
TargetCarbonic anhydrase(Stylophora pistillata)
Centre Scientifique de Monaco

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  3.94E+6nMAssay Description:Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5T7KPubMed
TargetCarbonic anhydrase 13(Mus musculus (mouse))
Universit£ degli Studi di Firenze

Curated by ChEMBL
LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  5.20E+6nMAssay Description:Inhibitory activity against mouse carbonic anhydrase XIII expressed in Escherichia coli TOP 10Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN09QFPubMed
TargetGamma carbonic anhydrase family protein(Vibrio cholerae)
Universit£ degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  7.90E+6nM ΔG°:  -11.8kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition of Vibrio cholerae recombinant carbonic anhydrase gamma expressed in Escherichia coli DE3 cells preincubated for 15 mins by stopped-flow C...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W9583BPubMed
TargetCarbonic anhydrase(Vibrio cholerae)
Universit£ degli Studi di Firenze

LigandPNGBDBM26990(CHEMBL1644699 | HS anion | HS(-1) | hydrogen(sulfi...)copy SMILEScopy InChI
Affinity DataKi:  2.13E+7nM ΔG°:  -9.38kJ/molepH: 7.5 T: 2°CAssay Description:Inhibition of Vibrio cholerae carbonic anhydrase beta preincubated for 15 mins by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W9583BPubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50498447(Acnaveen | Acnil | Bensulfoid | CHEBI:26833 | Cuti...)copy SMILEScopy InChI
Affinity DataEC50:  1.16E+5nMAssay Description:Activation of TRPA1 in rat astrocytes assessed as induction of Ca2+ influx by calcium green-1/acetoxymethyl ester-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N844ZPubMed
TargetOxytocin receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50147625(CHEBI:16136 | SULFUR, PRECIPITATED)copy SMILEScopy InChI
Affinity DataEC50:  0.120nMAssay Description:Agonist activity at human OTR expressed in CHO cells assessed as calcium mobilization measured after 30 mins by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8V9QPubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50147625(CHEBI:16136 | SULFUR, PRECIPITATED)copy SMILEScopy InChI
Affinity DataEC50: >100nMAssay Description:Agonist activity at human V1b receptor expressed in CHO cells assessed as calcium mobilization measured after 30 mins by Fluo-4-AM dye based FLIPR as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8V9QPubMed
TargetVasopressin V1a receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50147625(CHEBI:16136 | SULFUR, PRECIPITATED)copy SMILEScopy InChI
Affinity DataEC50: >100nMAssay Description:Agonist activity at human V1a receptor expressed in CHO cells assessed as calcium mobilization measured after 30 mins by Fluo-4-AM dye based FLIPR as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8V9QPubMed
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