Compile Data Set for Download or QSAR
Found 35 Enz. Inhib. hit(s) with Target = '3-phosphoinositide-dependent protein kinase 1 [48-359]'
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32447(Benzo[c][2,7]naphthyridine, 39)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32435(Benzo[c][2,7]naphthyridine, 28)copy SMILEScopy InChI
Affinity DataIC50: 26nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32450(Benzo[c][2,7]naphthyridine, 42)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32430(Benzo[c][2,7]naphthyridine, 24)copy SMILEScopy InChI
Affinity DataIC50: 35nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32433(Benzo[c][2,7]naphthyridine, 14)copy SMILEScopy InChI
Affinity DataIC50: 43nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32444(Benzo[c][2,7]naphthyridine, 36)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32449(Benzo[c][2,7]naphthyridine, 41)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32436(Benzo[c][2,7]naphthyridine, 29)copy SMILEScopy InChI
Affinity DataIC50: 57nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32437(Benzo[c][2,7]naphthyridine, 30)copy SMILEScopy InChI
Affinity DataIC50: 65nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32427(Benzo[c][2,7]naphthyridine, 21)copy SMILEScopy InChI
Affinity DataIC50: 66nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32445(Benzo[c][2,7]naphthyridine, 37)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32422(Benzo[c][2,7]naphthyridine, 9)copy SMILEScopy InChI
Affinity DataIC50: 70nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32441(Benzo[c][2,7]naphthyridine, 33)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32431(Benzo[c][2,7]naphthyridine, 25)copy SMILEScopy InChI
Affinity DataIC50: 74nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32448(Benzo[c][2,7]naphthyridine, 40)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32425(Benzo[c][2,7]naphthyridine, 12)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32428(Benzo[c][2,7]naphthyridine, 22)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32423(Benzo[c][2,7]naphthyridine, 10)copy SMILEScopy InChI
Affinity DataIC50: 108nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32446(Benzo[c][2,7]naphthyridine, 38)copy SMILEScopy InChI
Affinity DataIC50: 142nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32434(Benzo[c][2,7]naphthyridine, 27)copy SMILEScopy InChI
Affinity DataIC50: 144nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32432(Benzo[c][2,7]naphthyridine, 26)copy SMILEScopy InChI
Affinity DataIC50: 146nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32440(Benzo[c][2,7]naphthyridine, 32)copy SMILEScopy InChI
Affinity DataIC50: 283nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32443(Benzo[c][2,7]naphthyridine, 35)copy SMILEScopy InChI
Affinity DataIC50: 383nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32442(Benzo[c][2,7]naphthyridine, 34)copy SMILEScopy InChI
Affinity DataIC50: 434nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32451(Benzo[c][2,7]naphthyridine, 43)copy SMILEScopy InChI
Affinity DataIC50: 505nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32438(Benzo[c][2,7]naphthyridine, 31)copy SMILEScopy InChI
Affinity DataIC50: 532nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32418(Benzo[c][2,7]naphthyridine, 5)copy SMILEScopy InChI
Affinity DataIC50: 739nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32452(Benzo[c][2,7]naphthyridine, 44)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32426(Benzo[c][2,7]naphthyridine, 15)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32439(Benzo[c][2,7]naphthyridine, 16)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32420(Benzo[c][2,7]naphthyridine, 7)copy SMILEScopy InChI
Affinity DataIC50: 1.86E+3nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32424(Benzo[c][2,7]naphthyridine, 11)copy SMILEScopy InChI
Affinity DataIC50: 2.03E+3nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32421(Benzo[c][2,7]naphthyridine, 8)copy SMILEScopy InChI
Affinity DataIC50: 2.06E+3nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32429(Benzo[c][2,7]naphthyridine, 23)copy SMILEScopy InChI
Affinity DataIC50: 6.92E+3nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed
Target3-phosphoinositide-dependent protein kinase 1 [48-359](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM32419(Benzo[c][2,7]naphthyridine, 6)copy SMILEScopy InChI
Affinity DataIC50: 7.49E+3nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest differenti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CXJPubMed