Compile Data Set for Download or QSAR
Found 24 Enz. Inhib. hit(s) with Target = 'Coiled-coil domain-containing protein 6/Proto-oncogene tyrosine-protein kinase receptor Ret'
LigandPNGBDBM625349(US20230322769, Compound 58 | US20230322769, Compou...)copy SMILES
Affinity DataIC50: 0.340nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625352(US20230322769, Compound 65)copy SMILES
Affinity DataIC50: 0.520nMMore data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
LigandPNGBDBM625351(US20230322769, Compound 64 | US20230322769, Compou...)copy SMILES
Affinity DataIC50: 1.02nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625348(US20230322769, Compound 57 | US20230322769, Compou...)copy SMILES
Affinity DataIC50: 1.13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM296429(US10112942, Example 163 | US10112942, Example 166 ...)copy SMILEScopy InChI
Affinity DataIC50: 2.07nMMore data for this Ligand-Target Pair
LigandPNGBDBM625338(US20230322769, Compound 20)copy SMILES
Affinity DataIC50: 2.14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625346(US20230322769, Compound 51)copy SMILES
Affinity DataIC50: 2.15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625350(US20230322769, Compound 60 | US20230322769, Compou...)copy SMILES
Affinity DataIC50: 2.54nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625337(US20230322769, Compound 17)copy SMILES
Affinity DataIC50: 2.61nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625367(US20230322769, Compound 87 | US20230322769, Compou...)copy SMILES
Ligand InfoMCE
PC cidPC sid
In DepthDetails
LigandPNGBDBM625369(US20230322769, Compound 89)copy SMILES
Affinity DataIC50: 3.04nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625342(US20230322769, Compound 32)copy SMILES
Affinity DataIC50: 3.13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625335(US20230322769, Compound 16)copy SMILES
Affinity DataIC50: 3.65nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625348(US20230322769, Compound 57 | US20230322769, Compou...)copy SMILES
Affinity DataIC50: 4.44nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625358(US20230322769, Compound 78)copy SMILES
Affinity DataIC50: 4.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625350(US20230322769, Compound 60 | US20230322769, Compou...)copy SMILES
Affinity DataIC50: 6.01nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625347(US20230322769, Compound 55)copy SMILES
Affinity DataIC50: 7.45nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625349(US20230322769, Compound 58 | US20230322769, Compou...)copy SMILES
Affinity DataIC50: 8.07nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625351(US20230322769, Compound 64 | US20230322769, Compou...)copy SMILES
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625340(US20230322769, Compound 17-a)copy SMILES
Affinity DataIC50: 17.2nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625351(US20230322769, Compound 64 | US20230322769, Compou...)copy SMILES
Affinity DataIC50: 30.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625341(US20230322769, Compound 21)copy SMILES
Affinity DataIC50: 60.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM625343(US20230322769, Compound 34)copy SMILES
Affinity DataIC50: 71.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of CCDC6/RET (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation after 72 hrs by MTT assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J1054SPubMed