Compile Data Set for Download or QSAR
Found 123 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 2J2'
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50423541(DANAZOL | Danocrine | WIN-17757)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Mixed inhibition of recombinant CYP2J2 (unknown origin)-mediated astemizole O-demethylation in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN97D2PubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Non-competitive inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS method and Dixon plotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50043280(4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Non-competitive inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS method and Dixon plotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Non-competitive inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50183079(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)-1-(4-p...)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z440RPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50043280(4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...)copy SMILEScopy InChI
Affinity DataKi:  190nMAssay Description:Mixed type inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50088489(CHEMBL3527324)copy SMILEScopy InChI
Affinity DataKi:  2.40E+5nMAssay Description:Inhibition of recombinant CYP2J2 (unknown origin) treated with AMG 853More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z039WTPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50423541(DANAZOL | Danocrine | WIN-17757)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant CYP2J2 (unknown origin)-mediated astemizole O-demethylation preincubated for 30 mins followed by substrate addition in pres...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN97D2PubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50423541(DANAZOL | Danocrine | WIN-17757)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant CYP2J2 (unknown origin)-mediated astemizole O-demethylation in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN97D2PubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50423541(DANAZOL | Danocrine | WIN-17757)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant CYP2J2 (unknown origin)-mediated terfenadine hydroxylation in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN97D2PubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50423541(DANAZOL | Danocrine | WIN-17757)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP2J2 in human liver microsomes using 7 probe cocktail containing phenacetin, paclitaxel, diclofenac, S-mephenytoin, dextromethorphan,...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN97D2PubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50423541(DANAZOL | Danocrine | WIN-17757)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP2J2-mediated astemizole O-demethylation in human liver microsomes after 8 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN97D2PubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50183079(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)-1-(4-p...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z440RPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50183075(1-(4-allylphenyl)-4-(4-(hydroxydiphenylmethyl)pipe...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z440RPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50043280(4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50043280(4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation reduction in astemizole O-demethylation after 30 mins by L...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50043280(4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation after 30 mins by LC-MS/MS method in presence of 1 mM NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM31772(1-[2-(2,4-dichlorobenzyl)oxy-2-(2,4-dichlorophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of CYP2J2-mediated astemizole O-demethylation in human liver microsomes after 8 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN97D2PubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50183085(1-(4-ethylphenyl)-4-(4-(hydroxydiphenylmethyl)pipe...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z440RPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM31772(1-[2-(2,4-dichlorobenzyl)oxy-2-(2,4-dichlorophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Inhibition of CYP2J2 in human liver microsomes using 7 probe cocktail containing phenacetin, paclitaxel, diclofenac, S-mephenytoin, dextromethorphan,...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN97D2PubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50183084(CHEMBL205154 | terfenadone)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z440RPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50183080(1-(4-butylphenyl)-4-(4-(hydroxydiphenylmethyl)pipe...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z440RPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50183082(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)-1-p-to...)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z440RPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation after 30 mins by LC-MS/MS method in presence of 1 mM NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)copy SMILEScopy InChI
Affinity DataIC50: 940nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation reduction in astemizole O-demethylation after 30 mins by L...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50041457(4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 990nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50017376((+/-)1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylm...)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of CYP2J2-mediated astemizole O-demethylation in human liver microsomes after 8 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN97D2PubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50183077(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)-1-(4-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z440RPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305628(CHEMBL589135 | N-(2,4-dichlorobenzyl)-4-phenoxypip...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP2J2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SZ6PubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305628(CHEMBL589135 | N-(2,4-dichlorobenzyl)-4-phenoxypip...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of CYP2J2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639QTCPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50101815(CHEBI:7550 | Nicardipine)copy SMILEScopy InChI
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50017376((+/-)1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylm...)copy SMILEScopy InChI
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of CYP2J2 in human liver microsomes using 7 probe cocktail containing phenacetin, paclitaxel, diclofenac, S-mephenytoin, dextromethorphan,...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN97D2PubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50183078(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)-1-(4-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z440RPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50319984(4-(pyrimidin-2-yloxy)-N-(2-(trifluoromethoxy)benzy...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP2J2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GTJPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50297412(CHEMBL560740 | N-[3,3-Bis-(4-fluorophenyl)-propyl]...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP2J2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2P2GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM78934(2-methoxyacetic acid [(1S,2S)-2-[2-[3-(1H-benzimid...)copy SMILEScopy InChI
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50183076(1-(4-(2,2-difluoroethyl)phenyl)-4-(4-(hydroxydiphe...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z440RPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50183086(3-(4-(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)b...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z440RPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50045000((NFLX)1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-...)copy SMILEScopy InChI
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50319982(CHEMBL1085746 | N-(2,4-dichlorobenzyl)-4-(pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of CYP2J2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7GTJPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50297400((S)-4-Cyano-N-[3-(4-fluorophenyl)-3-(4-methanesulf...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP2J2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BG2P2GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50101817(Adalat | Adalat Cc | Afeditab Cr | BAY-A-1040 | CH...)copy SMILEScopy InChI
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50101971(BAY-E-9736 | CHEBI:7575 | Nimodipine | Nimotop)copy SMILEScopy InChI
Affinity DataIC50: 3.38E+3nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50183081(1-(4-bromophenyl)-4-(4-(hydroxydiphenylmethyl)pipe...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z440RPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50158460((3,5-dibromo-4-hydroxyphenyl)(2-ethyl-1-benzofuran...)copy SMILEScopy InChI
Affinity DataIC50: 4.26E+3nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataIC50: 4.69E+3nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM25756((2R,3R)-2,3-dihydroxysuccinic acid;1-(isopropylami...)copy SMILEScopy InChI
Affinity DataIC50: 4.87E+3nMAssay Description:Inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM235143(US9359341, Formula B)copy SMILEScopy InChI
Affinity DataIC50: 6.70E+3nMpH: 7.4 T: 2°CAssay Description:Incubation of phenacetin, diclofenac, dextromethorphan, mephenotoin, albendazole and testosterone with human liver microsomes in the presence of in e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29Z93S1US Patent
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50183087(1-(benzo[d][1,3]dioxol-5-yl)-4-(4-(hydroxydiphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z440RPubMed
Displayed 1 to 50 (of 123 total ) | Next | Last >>
Jump to: