Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with Target = 'DNA helicase [35-727]'
TargetDNA helicase [35-727](Plasmodium falciparum)
International Centre for Genetic Engineering and Biotechnology

LigandPNGBDBM32017((7S,9S)-7-[(2R,4S,5S,6S)-4-azanyl-6-methyl-5-oxida...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMpH: 8.0 T: 2°CAssay Description:Helicase assay was demonstrated using the purified fraction of PfUDN. The specially designed partial duplex substrate consisted of a 32P-labelled 47-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7F45PubMed
TargetDNA helicase [35-727](Plasmodium falciparum)
International Centre for Genetic Engineering and Biotechnology

LigandPNGBDBM200295(AB00053825_07 | Ethidium bromide | cid_3624)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMpH: 8.0 T: 2°CAssay Description:The hydrolysis of ATP catalyzed by PfUDN was assayed by measuring the formation of Pi from [γ-32P] ATP. The reaction mixture of 10 μl conta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7F45PubMed
TargetDNA helicase [35-727](Plasmodium falciparum)
International Centre for Genetic Engineering and Biotechnology

LigandPNGBDBM50055660(1-amino-3-(4-(4-(2-(amino(iminio)methylamino)aceta...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMpH: 8.0 T: 2°CAssay Description:The hydrolysis of ATP catalyzed by PfUDN was assayed by measuring the formation of Pi from [γ-32P] ATP. The reaction mixture of 10 μl conta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7F45PubMed
TargetDNA helicase [35-727](Plasmodium falciparum)
International Centre for Genetic Engineering and Biotechnology

LigandPNGBDBM50370548(NOGALAMYCIN)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMpH: 8.0 T: 2°CAssay Description:The hydrolysis of ATP catalyzed by PfUDN was assayed by measuring the formation of Pi from [γ-32P] ATP. The reaction mixture of 10 μl conta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7F45PubMed
TargetDNA helicase [35-727](Plasmodium falciparum)
International Centre for Genetic Engineering and Biotechnology

LigandPNGBDBM50370548(NOGALAMYCIN)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMpH: 8.0 T: 2°CAssay Description:Helicase assay was demonstrated using the purified fraction of PfUDN. The specially designed partial duplex substrate consisted of a 32P-labelled 47-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7F45PubMed
TargetDNA helicase [35-727](Plasmodium falciparum)
International Centre for Genetic Engineering and Biotechnology

LigandPNGBDBM32017((7S,9S)-7-[(2R,4S,5S,6S)-4-azanyl-6-methyl-5-oxida...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMpH: 8.0 T: 2°CAssay Description:The hydrolysis of ATP catalyzed by PfUDN was assayed by measuring the formation of Pi from [γ-32P] ATP. The reaction mixture of 10 μl conta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7F45PubMed
TargetDNA helicase [35-727](Plasmodium falciparum)
International Centre for Genetic Engineering and Biotechnology

LigandPNGBDBM50055660(1-amino-3-(4-(4-(2-(amino(iminio)methylamino)aceta...)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMpH: 8.0 T: 2°CAssay Description:Helicase assay was demonstrated using the purified fraction of PfUDN. The specially designed partial duplex substrate consisted of a 32P-labelled 47-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7F45PubMed
TargetDNA helicase [35-727](Plasmodium falciparum)
International Centre for Genetic Engineering and Biotechnology

LigandPNGBDBM200295(AB00053825_07 | Ethidium bromide | cid_3624)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMpH: 8.0 T: 2°CAssay Description:Helicase assay was demonstrated using the purified fraction of PfUDN. The specially designed partial duplex substrate consisted of a 32P-labelled 47-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7F45PubMed
TargetDNA helicase [35-727](Plasmodium falciparum)
International Centre for Genetic Engineering and Biotechnology

LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)copy SMILEScopy InChI
Affinity DataIC50: 9.90E+3nMpH: 8.0 T: 2°CAssay Description:The hydrolysis of ATP catalyzed by PfUDN was assayed by measuring the formation of Pi from [γ-32P] ATP. The reaction mixture of 10 μl conta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7F45PubMed