Compile Data Set for Download or QSAR
Found 14 Enz. Inhib. hit(s) with Target = 'DNA repair protein RAD52 homolog'
TargetDNA repair protein RAD52 homolog(Homo sapiens)TBA
LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)copy SMILEScopy InChI
Affinity DataIC50: 277nMAssay Description:Inhibition of 6His-tagged human RD52 assessed as reduction in RD52 binding to Cy3-dT30-Cy5 ssDNA incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4G9MPubMed
TargetDNA repair protein RAD52 homolog(Homo sapiens)TBA
LigandPNGBDBM50436204(CHEMBL109037)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4G9MPubMed
TargetDNA repair protein RAD52 homolog(Homo sapiens)TBA
LigandPNGBDBM50565810(Strictinin)copy SMILES
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of 6His-tagged human RD52 assessed as reduction in RD52 binding to Cy3-dT30-Cy5 ssDNA incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4G9MPubMed
TargetDNA repair protein RAD52 homolog(Homo sapiens)TBA
LigandPNGBDBM50187665((-)-epigallocatechin | CHEMBL47386)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of 6His-tagged human RD52 assessed as reduction in RD52 binding to Cy3-dT30-Cy5 ssDNA incubated for 30 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4G9MPubMed
TargetDNA repair protein RAD52 homolog(Homo sapiens)TBA
LigandPNGBDBM50565805(CHEMBL4785153)copy SMILES
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4G9MPubMed
TargetDNA repair protein RAD52 homolog(Homo sapiens)TBA
LigandPNGBDBM50565806(CHEMBL4795092)copy SMILES
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4G9MPubMed
TargetDNA repair protein RAD52 homolog(Homo sapiens)TBA
LigandPNGBDBM50565808(CHEMBL4785369)copy SMILES
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4G9MPubMed
TargetDNA repair protein RAD52 homolog(Homo sapiens)TBA
LigandPNGBDBM23223(7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4G9MPubMed
TargetDNA repair protein RAD52 homolog(Homo sapiens)TBA
LigandPNGBDBM50565809(CHEMBL1718911)copy SMILES
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human RAD52 assessed as reduction in DNA annealing using tailed ds-DNA 337-F/1337-BHQ1 by fluorescence-quenching assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4G9MPubMed
TargetDNA repair protein RAD52 homolog(Homo sapiens)TBA
LigandPNGBDBM50565804(CHEMBL4796552)copy SMILES
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4G9MPubMed
TargetDNA repair protein RAD52 homolog(Homo sapiens)TBA
LigandPNGBDBM50565803(CHEMBL4777728)copy SMILES
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4G9MPubMed
TargetDNA repair protein RAD52 homolog(Homo sapiens)TBA
LigandPNGBDBM50565802(CHEMBL4165444 | US11584714, Compound 29)copy SMILES
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4G9MPubMed
TargetDNA repair protein RAD52 homolog(Homo sapiens)TBA
LigandPNGBDBM60996(5-[(3-carboxy-4-hydroxy-phenyl)-(3-carboxy-4-keto-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4G9MPubMed
TargetDNA repair protein RAD52 homolog(Homo sapiens)TBA
LigandPNGBDBM50565807(CHEMBL4785174)copy SMILES
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of FAM-conjugated ssDNA binding to His-tagged wild type RAD52 (unknown origin) expressed in Rosetta2(DE3)/pLysS cells measured after 30 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GX4G9MPubMed