Compile Data Set for Download or QSAR
Found 263 Enz. Inhib. hit(s) with Target = 'Dual specificity mitogen-activated protein kinase kinase 4'
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Mitogen activated protein kinase kinase 4More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WW7JD9PubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50567689(CHEMBL4790247)copy SMILES
Affinity DataIC50: 29nMAssay Description:Inhibition of MKK4 (unknown origin) by PanQinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6X0KPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50559798(CHEMBL4758063 | US11370770, Compound 6ff)copy SMILES
Affinity DataIC50: 41nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50559798(CHEMBL4758063 | US11370770, Compound 6ff)copy SMILES
Affinity DataIC50: 41nMAssay Description:Inhibition of MEK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028W77PubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558862(US11370770, Compound 6n)copy SMILES
Affinity DataIC50: 60nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50577661(CHEMBL4879048)copy SMILES
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant full length N-terminal GST tagged MEK4 expressed in Sf21 cells using p38 alpha as substrate pre-incubated for 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50MCPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558880(US11370770, Compound 6ee)copy SMILES
Affinity DataIC50: 63nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50559798(CHEMBL4758063 | US11370770, Compound 6ff)copy SMILES
Affinity DataIC50: 66nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50577689(CHEMBL4866649)copy SMILES
Affinity DataIC50: 83nMAssay Description:Inhibition of human recombinant full length N-terminal GST tagged MEK4 expressed in Sf21 cells using p38 alpha as substrate pre-incubated for 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50MCPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50567688(CHEMBL4784779)copy SMILES
Affinity DataIC50: 89nMAssay Description:Inhibition of MKK4 (unknown origin) by PanQinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6X0KPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50577657(CHEMBL4848865)copy SMILES
Affinity DataIC50: 96nMAssay Description:Inhibition of human recombinant full length N-terminal GST tagged MEK4 expressed in Sf21 cells using p38 alpha as substrate pre-incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50MCPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50559798(CHEMBL4758063 | US11370770, Compound 6ff)copy SMILES
Affinity DataIC50: 100nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558875(US11370770, Compound 6z)copy SMILES
Affinity DataIC50: 100nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558864(US11370770, Compound 6p)copy SMILES
Affinity DataIC50: 110nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558878(US11370770, Compound 6cc)copy SMILES
Affinity DataIC50: 120nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558862(US11370770, Compound 6n)copy SMILES
Affinity DataIC50: 130nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50585046(CHEMBL5086263)copy SMILES
Affinity DataIC50: 132nMAssay Description:Inhibition of MEK4 (unknown origin) at 1 uM by kinome scan methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183BDBPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50567686(CHEMBL4798975)copy SMILES
Affinity DataIC50: 146nMAssay Description:Inhibition of MKK4 (unknown origin) by PanQinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6X0KPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558867(US11370770, Compound 6s)copy SMILES
Affinity DataIC50: 150nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50585045(CHEMBL5093741)copy SMILES
Affinity DataIC50: 173nMAssay Description:Inhibition of MEK4 (unknown origin) at 1 uM by kinome scan methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183BDBPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558848(US11370770, Compound 6a)copy SMILES
Affinity DataIC50: 180nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558867(US11370770, Compound 6s)copy SMILES
Affinity DataIC50: 180nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50559799(CHEMBL4748767)copy SMILES
Affinity DataIC50: 190nMAssay Description:Inhibition of MEK4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028W77PubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558866(US11370770, Compound 6r)copy SMILES
Affinity DataIC50: 200nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558865(US11370770, Compound 6q)copy SMILES
Affinity DataIC50: 210nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558867(US11370770, Compound 6s)copy SMILES
Affinity DataIC50: 220nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558858(US11370770, Compound 6j)copy SMILES
Affinity DataIC50: 240nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558858(US11370770, Compound 6j)copy SMILES
Affinity DataIC50: 250nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558880(US11370770, Compound 6ee)copy SMILES
Affinity DataIC50: 260nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50607924(CHEMBL5278864)copy SMILES
Affinity DataIC50: 281nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50577686(CHEMBL4865159)copy SMILES
Affinity DataIC50: 290nMAssay Description:Inhibition of human recombinant full length N-terminal GST tagged MEK4 expressed in Sf21 cells using p38 alpha as substrate pre-incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50MCPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50577647(CHEMBL4849172)copy SMILES
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant full length N-terminal GST tagged MEK4 expressed in Sf21 cells using p38 alpha as substrate pre-incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50MCPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50577671(CHEMBL4872723)copy SMILES
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant full length N-terminal GST tagged MEK4 expressed in Sf21 cells using p38 alpha as substrate pre-incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50MCPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558875(US11370770, Compound 6z)copy SMILES
Affinity DataIC50: 360nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50577673(CHEMBL4858450)copy SMILES
Affinity DataIC50: 380nMAssay Description:Inhibition of human recombinant full length N-terminal GST tagged MEK4 expressed in Sf21 cells using p38 alpha as substrate pre-incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50MCPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50577682(CHEMBL4846360)copy SMILES
Affinity DataIC50: 390nMAssay Description:Inhibition of human recombinant full length N-terminal GST tagged MEK4 expressed in Sf21 cells using p38 alpha as substrate pre-incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50MCPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558863(US11370770, Compound 6o)copy SMILES
Affinity DataIC50: 390nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM19459(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant human MEK4 (14 to 377 residues) after 5 mins by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2028W77PubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558865(US11370770, Compound 6q)copy SMILES
Affinity DataIC50: 410nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558864(US11370770, Compound 6p)copy SMILES
Affinity DataIC50: 410nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558879(US11370770, Compound 6dd)copy SMILES
Affinity DataIC50: 420nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50577680(CHEMBL4874017)copy SMILES
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant full length N-terminal GST tagged MEK4 expressed in Sf21 cells using p38 alpha as substrate pre-incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50MCPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50577674(CHEMBL4871499)copy SMILES
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant full length N-terminal GST tagged MEK4 expressed in Sf21 cells using p38 alpha as substrate pre-incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50MCPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558848(US11370770, Compound 6a)copy SMILES
Affinity DataIC50: 460nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558876(US11370770, Compound 6aa)copy SMILES
Affinity DataIC50: 460nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558862(US11370770, Compound 6n)copy SMILES
Affinity DataIC50: 470nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50577685(CHEMBL4854291)copy SMILES
Affinity DataIC50: 470nMAssay Description:Inhibition of human recombinant full length N-terminal GST tagged MEK4 expressed in Sf21 cells using p38 alpha as substrate pre-incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50MCPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50577659(CHEMBL4860404)copy SMILES
Affinity DataIC50: 480nMAssay Description:Inhibition of human recombinant full length N-terminal GST tagged MEK4 expressed in Sf21 cells using p38 alpha as substrate pre-incubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50MCPubMed
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558866(US11370770, Compound 6r)copy SMILES
Affinity DataIC50: 510nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
TargetDual specificity mitogen-activated protein kinase kinase 4(Homo sapiens (Human))
Millennium Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM558866(US11370770, Compound 6r)copy SMILES
Affinity DataIC50: 560nMAssay Description:Kinase activity of recombinant active full-length human MEK4 (Carna Biosciences) was measured using the ADP-Glo assay (Promega) with 3 μM recomb...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1GWDUS Patent
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