Found 24 Enz. Inhib. hit(s) with Target = 'Dual specificity protein phosphatase 5' TargetDual specificity protein phosphatase 5 [180-384](Homo sapiens (Human))
Texas Wesleyan University
Texas Wesleyan University
Affinity DataKi: 25nM ΔG°: -43.4kJ/mole IC50: 4.40E+4nMT: 2°CAssay Description:For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:This assay was done with full-length protein (containing both domains), andusing pERK as substrate.More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+3nMAssay Description:This assay was done with full-length protein (containing both domains), andusing pERK as substrate.More data for this Ligand-Target Pair
Affinity DataIC50: 5.90E+3nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 1.65E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 2.28E+4nMAssay Description:This assay was done with full-length protein (containing both domains), andusing pERK as substrate.More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.25E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.45E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.65E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.69E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 7.85E+4nMpH: 7.5 T: 2°CAssay Description:Briefly, assays without and with inhibitors were performed in Greiner 96-well clear bottom plates with a total assay volume of 200 μL. The assay...More data for this Ligand-Target Pair
Affinity DataIC50: 7.88E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 8.66E+4nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 2.21E+5nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+5nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 5.88E+5nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
Affinity DataIC50: 7.25E+5nMpH: 7.5 T: 2°CAssay Description:Upon the addition of 4 μL of these respective inhibitor stock solutions to the assay buffer, the resulting range in assay inhibitor concentratio...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 5 [180-384](Homo sapiens (Human))
Texas Wesleyan University
Texas Wesleyan University
Affinity DataIC50: 5.10E+6nMT: 2°CAssay Description:For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 5 [180-384](Homo sapiens (Human))
Texas Wesleyan University
Texas Wesleyan University
Affinity DataIC50: 6.40E+6nMT: 2°CAssay Description:For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 5 [180-384](Homo sapiens (Human))
Texas Wesleyan University
Texas Wesleyan University
Affinity DataIC50: 1.60E+7nMT: 2°CAssay Description:For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 5 [180-384](Homo sapiens (Human))
Texas Wesleyan University
Texas Wesleyan University
Affinity DataIC50: 2.60E+7nMT: 2°CAssay Description:For the 96-well plate validation assay, sodium orthovanadate (Sigma Aldrich) was utilized as a positive control for inhibition [Swarup et al., Bioche...More data for this Ligand-Target Pair
