Found 139 Enz. Inhib. hit(s) with Target = 'Ectonucleotide pyrophosphatase/phosphodiesterase family member 3'
Affinity DataKi: 6.81E+4nMAssay Description:Competitive inhibition of human NPP3 using ATP as substrateMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Bos taurus)
University of Campinas
Curated by ChEMBL
University of Campinas
Curated by ChEMBL
Affinity DataKi: 1.40E+6nMAssay Description:Inhibition of bovine intestinal 5'-nucleotide phosphodiesterase using 4-nitrophenyl phenylphosphonate substrate by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant NPP3 expressed in COS-7 cell membrane at 100 uM using p-nitrophenyl thymidine monophosphate substrate incubated for 3...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant NPP3 expressed in COS-7 cell membrane at 100 uM using p-nitrophenyl thymidine monophosphate substrate incubated for 3...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of NPP3 (unknown origin) transfected in COS7 cells using pNP-TMP as substrate incubated for 35 mins by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 214nMAssay Description:Inhibition of human NPP3 expressed in African green monkey COS7 cell membranes pre-incubated for 10 mins before pNP-TMP substrate addition and furthe...More data for this Ligand-Target Pair