Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Flap endonuclease 1 [1-336]'
TargetFlap endonuclease 1 [1-336](Homo sapiens (Human))
University of Sheffield

LigandPNGBDBM197162(3-hydroxy-1-(4-methoxybenzyl)quinazoline-2,4(1H,3H...)copy SMILEScopy InChI
Affinity DataIC50: 16.9nMpH: 7.5Assay Description:Reaction mixtures containing twelve different concentrations of FAM-labeled DF1 (Supplementary Fig. 5a) substrate were prepared in reaction buffer (R...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H88PubMed
TargetFlap endonuclease 1 [1-336](Homo sapiens (Human))
University of Sheffield

LigandPNGBDBM197161(1-(cyclopropylmethyl)-3-hydroxyquinazoline-2,4(1H,...)copy SMILEScopy InChI
Affinity DataIC50: 30nMpH: 7.5Assay Description:Reaction mixtures containing twelve different concentrations of FAM-labeled DF1 (Supplementary Fig. 5a) substrate were prepared in reaction buffer (R...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4H88PubMed
TargetFlap endonuclease 1 [1-336](Homo sapiens (Human))
University of Sheffield

LigandPNGBDBM50157840(1-((2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 46.4nMpH: 7.5Assay Description:Reaction mixtures containing twelve different concentrations of FAM-labeled DF1 (Supplementary Fig. 5a) substrate were prepared in reaction buffer (R...More data for this Ligand-Target Pair