Compile Data Set for Download or QSAR
Found 156 Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2'
LigandPNGBDBM25878(5-(2-fluorophenyl)-1-methyl-7-nitro-2,3-dihydro-1H...)copy SMILEScopy InChI
Affinity DataKi:  2.5nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B35B0PubMed
LigandPNGBDBM26267(RO-154513 | Ro15-4513 | [3H]Ro15-4513 | ethyl 12-a...)copy SMILEScopy InChI
Affinity DataKi:  2.60nMAssay Description:Binding affinity for human GABA-A receptor alpha-2-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
LigandPNGBDBM50049737(5-Methyl-6-oxo-8-propa-1,2-dienyl-5,6-dihydro-4H-2...)copy SMILEScopy InChI
Affinity DataKi:  7.20nMAssay Description:Binding affinity for human GABA-A receptor alpha-2-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35SR6PubMed
LigandPNGBDBM50083911(7-Bromo-1-methyl-5-phenyl-1,3-dihydro-benzo[e][1,4...)copy SMILEScopy InChI
Affinity DataKi:  9.30nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B35B0PubMed
LigandPNGBDBM50044947(8-Bromo-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tria...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Binding affinity for human GABA-A receptor alpha-2-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35SR6PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Rattus norvegicus (Rat))
Università di Pisa

Curated by ChEMBL
LigandPNGBDBM50165326(8-Chloro-2-phenyl-5H-3,3a,5,9b-tetraaza-cyclopenta...)copy SMILEScopy InChI
Affinity DataKi:  13.9nMAssay Description:Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha2-beta2-gamma2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994QVPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Rattus norvegicus (Rat))
Università di Pisa

Curated by ChEMBL
LigandPNGBDBM50165325(2-(4-Methoxy-phenyl)-5H-3,3a,5,9b-tetraaza-cyclope...)copy SMILEScopy InChI
Affinity DataKi:  14.3nMAssay Description:Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha2-beta2-gamma2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994QVPubMed
LigandPNGBDBM50034839(8-Chloro-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tri...)copy SMILEScopy InChI
Affinity DataKi:  16.3nMAssay Description:Binding affinity to human recombinant GABA alpha2beta2gamma2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21R6QRBPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Rattus norvegicus (Rat))
Università di Pisa

Curated by ChEMBL
LigandPNGBDBM50165329(8-Chloro-2-(4-methoxy-phenyl)-5H-3,3a,5,9b-tetraaz...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha2-beta2-gamma2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994QVPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Rattus norvegicus (Rat))
Università di Pisa

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
LigandPNGBDBM25877(CHEMBL286594 | RY-80, 1 | ethyl 12-ethynyl-8-methy...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Binding affinity for human GABA-A receptor alpha-2-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35SR6PubMed
LigandPNGBDBM50049740(5-Methyl-6-oxo-8-prop-1-ynyl-5,6-dihydro-4H-2,5,10...)copy SMILEScopy InChI
Affinity DataKi:  22nMAssay Description:Binding affinity for human GABA-A receptor alpha-2-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35SR6PubMed
LigandPNGBDBM50049736(8-Ethynyl-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tr...)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:Binding affinity for human GABA-A receptor alpha-2-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35SR6PubMed
LigandPNGBDBM50049734(8-Ethyl-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tria...)copy SMILEScopy InChI
Affinity DataKi:  27nMAssay Description:Binding affinity for human GABA-A receptor alpha-2-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35SR6PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Rattus norvegicus (Rat))
Università di Pisa

Curated by ChEMBL
LigandPNGBDBM50165328(2-Phenyl-5H-3,3a,5,9b-tetraaza-cyclopenta[a]naphth...)copy SMILEScopy InChI
Affinity DataKi:  27.6nMAssay Description:Displacement of [3H]-flumazenil from rat GABA-A Gamma-aminobutyric acid A receptor alpha2-beta2-gamma2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H994QVPubMed
LigandPNGBDBM50083894(7-Ethynyl-1-methyl-5-phenyl-1,3-dihydro-benzo[e][1...)copy SMILEScopy InChI
Affinity DataKi:  42nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B35B0PubMed
LigandPNGBDBM50049739(8-Ethyl-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-tria...)copy SMILEScopy InChI
Affinity DataKi:  56nMAssay Description:Binding affinity for human GABA-A receptor alpha-2-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35SR6PubMed
LigandPNGBDBM50485822(CHEMBL2170373)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Displacement of [3H]flumazenil from human recombinant GABA-A alpha2beta2gamma2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134W2PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Rattus norvegicus (Rat))
Università di Pisa

Curated by ChEMBL
LigandPNGBDBM50206941(CHEMBL376508 | N-(4-bromobenzyl)-2-(1H-indol-3-yl)...)copy SMILEScopy InChI
Affinity DataKi:  81nMAssay Description:Displacement of [3H]flumazenil from rat GABAA alpha2beta2gamma2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9376QPubMed
LigandPNGBDBM50485821(CHEMBL2170370)copy SMILEScopy InChI
Affinity DataKi:  105nMAssay Description:Displacement of [3H]flumazenil from human recombinant GABA-A alpha2beta2gamma2L receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H134W2PubMed
LigandPNGBDBM50019266(1-Methyl-5-phenyl-1,3-dihydro-benzo[e][1,4]diazepi...)copy SMILEScopy InChI
Affinity DataKi:  138nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B35B0PubMed
LigandPNGBDBM50049738(5-Methyl-6-oxo-8-trimethylsilanylethynyl-5,6-dihyd...)copy SMILEScopy InChI
Affinity DataKi:  142nMAssay Description:Binding affinity for human GABA-A receptor alpha-2-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35SR6PubMed
LigandPNGBDBM50049735(5-Methyl-6-oxo-8-trimethylsilanylethynyl-5,6-dihyd...)copy SMILEScopy InChI
Affinity DataKi:  143nMAssay Description:Binding affinity for human GABA-A receptor alpha-2-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35SR6PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Rattus norvegicus (Rat))
Università di Pisa

Curated by ChEMBL
LigandPNGBDBM50185264(CHEMBL204841 | N-((1H-pyrrol-3-yl)methyl)-2-(5-nit...)copy SMILEScopy InChI
Affinity DataKi:  154nMAssay Description:Displacement of [3H]flumazenil from rat GABA-Aalpha2 receptor plus beta-2-gamma-2 in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B038FPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Rattus norvegicus (Rat))
Università di Pisa

Curated by ChEMBL
LigandPNGBDBM50370710(CHEMBL1162923)copy SMILEScopy InChI
Affinity DataKi:  155nMAssay Description:Displacement of [3H]flumazenil from rat GABA-Aalpha2 receptor plus beta-2-gamma-2 in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B038FPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Rattus norvegicus (Rat))
Università di Pisa

Curated by ChEMBL
LigandPNGBDBM26266(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)copy SMILEScopy InChI
Affinity DataKi:  156nMAssay Description:Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Rattus norvegicus (Rat))
Università di Pisa

Curated by ChEMBL
LigandPNGBDBM50206936(CHEMBL375367 | N-isopropyl-2-(5-nitro-1H-indol-3-y...)copy SMILEScopy InChI
Affinity DataKi:  175nMAssay Description:Displacement of [3H]flumazenil from rat GABAA alpha2beta2gamma2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K9376QPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Rattus norvegicus (Rat))
Università di Pisa

Curated by ChEMBL
LigandPNGBDBM50122841(3-(3H-1lambda*4*-Thiophen-3-yl)-6-thiophen-3-yl-4H...)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70F59PubMed
LigandPNGBDBM50083899(5-Phenyl-1,3-dihydro-benzo[e][1,4]diazepin-2-one |...)copy SMILEScopy InChI
Affinity DataKi:  233nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B35B0PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Rattus norvegicus (Rat))
Università di Pisa

Curated by ChEMBL
LigandPNGBDBM50185269(CHEMBL203629 | N-(furan-3-ylmethyl)-2-(5-nitro-1H-...)copy SMILEScopy InChI
Affinity DataKi:  236nMAssay Description:Displacement of [3H]flumazenil from rat GABA-Aalpha2 receptor plus beta-2-gamma-2 in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B038FPubMed
LigandPNGBDBM50214664(5-chloromethyl-1-(2,6-dichloro-4-trifluoromethylph...)copy SMILEScopy InChI
Affinity DataKi:  266nMAssay Description:Displacement of [3H]EBOB from human recombinant GABA alpha-1-beta-2-gamma-2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64HS0PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Rattus norvegicus (Rat))
Università di Pisa

Curated by ChEMBL
LigandPNGBDBM50122840(3-(3-Bromo-phenyl)-6-thiophen-3-yl-4H-pyrazolo[1,5...)copy SMILEScopy InChI
Affinity DataKi:  291nMAssay Description:Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70F59PubMed
LigandPNGBDBM50049733(5-Methyl-6-oxo-8-(3-trimethylsilanyl-prop-1-ynyl)-...)copy SMILEScopy InChI
Affinity DataKi: >300nMAssay Description:Binding affinity for human GABA-A receptor alpha-2-beta-2-gamma-2 expressed in L(tk-) cell membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35SR6PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Rattus norvegicus (Rat))
Università di Pisa

Curated by ChEMBL
LigandPNGBDBM50122847(3-Pyridin-3-yl-6-thiophen-3-yl-4H-pyrazolo[1,5-a]p...)copy SMILEScopy InChI
Affinity DataKi:  315nMAssay Description:Binding affinity for recombinant rat GABA-A receptor alpha2-beta2-gamma2 subunits expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70F59PubMed
Displayed 1 to 50 (of 156 total ) | Next | Last >>
Jump to: