Compile Data Set for Download or QSAR
Found 49 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1/11/4/6/8'
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65470(Quinolone-based HDAC inhibitor 4i)copy SMILEScopy InChI
Affinity DataIC50: 0.100nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65471(Quinolone-based HDAC inhibitor 4j)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65478(Quinolone-based HDAC inhibitor 4o)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65479(Quinolone-based HDAC inhibitor 4p)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65481(Quinolone-based HDAC inhibitor 4r)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65475(Quinolone-based HDAC inhibitor 4l)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65474(Quinolone-based HDAC inhibitor 4k)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65458(Quinolone-based HDAC inhibitor 4a)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65485(Quinolone-based HDAC inhibitor 4v)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65463(Quinolone-based HDAC inhibitor 4c)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65480(Quinolone-based HDAC inhibitor 4q)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65469(Quinolone-based HDAC inhibitor 4h)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206287((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(p-tolylamino)pr...)copy SMILES
Affinity DataIC50: 74nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65476(Quinolone-based HDAC inhibitor 4m)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206286((S)-N1-(3-(1H-indol-3-yl)-1-((4-iodophenyl)amino)-...)copy SMILES
Affinity DataIC50: 78nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65484(Quinolone-based HDAC inhibitor 4u)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65468(Quinolone-based HDAC inhibitor 4g)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65472(Quinolone-based HDAC inhibitor 4w)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206285((S)-N1-(1-((4-bromophenyl)amino)-3-(1H-indol-3-yl)...)copy SMILES
Affinity DataIC50: 96nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65464(Quinolone-based HDAC inhibitor 4d)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)copy SMILEScopy InChI
Affinity DataIC50: 131nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65477(Quinolone-based HDAC inhibitor 4n)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206284((S)-N1-(1-((4-chlorophenyl)amino)-3-(1H-indol-3-yl...)copy SMILES
Affinity DataIC50: 150nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206281((S)-N1-(1-((3-bromophenyl)amino)-3-(1H-indol-3-yl)...)copy SMILES
Affinity DataIC50: 189nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206283((S)-N1-(1-((4-fluorophenyl)amino)-3-(1H-indol-3-yl...)copy SMILES
Affinity DataIC50: 202nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206278((S)-N1-(3-(1H-indol-3-yl)-1-((naphthalen-1-ylmethy...)copy SMILES
Affinity DataIC50: 225nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206267((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(propylamino)pro...)copy SMILES
Affinity DataIC50: 227nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65483(Quinolone-based HDAC inhibitor 4t)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206279((S)-N1-(1-((3-fluorophenyl)amino)-3-(1H-indol-3-yl...)copy SMILES
Affinity DataIC50: 234nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65459(Quinolone-based HDAC inhibitor 4b)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206277((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(phenethylamino)...)copy SMILES
Affinity DataIC50: 301nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65482(Quinolone-based HDAC inhibitor 4s)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206289((S)-N1-(1-((4-ethoxyphenyl)amino)-3-(1H-indol-3-yl...)copy SMILES
Affinity DataIC50: 335nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206276((S)-N1-(1-(benzylamino)-3-(1H-indol-3-yl)-1-oxopro...)copy SMILES
Affinity DataIC50: 346nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206280((S)-N1-(1-((3-chlorophenyl)amino)-3-(1H-indol-3-yl...)copy SMILES
Affinity DataIC50: 360nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206275((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(phenylamino)pro...)copy SMILES
Affinity DataIC50: 361nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65467(Quinolone-based HDAC inhibitor 4f)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM65466(Quinolone-based HDAC inhibitor 4e)copy SMILEScopy InChI
Affinity DataIC50: 410nMAssay Description:Histone Deacetylase (HDAC) Inhibition Assay using Boc-Lys(Ac)-AMC Substrate: Inhibition of HDAC has been implicated to modulate transcription and to ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6916PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206288((S)-N1-(3-(1H-indol-3-yl)-1-((4-methoxyphenyl)amin...)copy SMILES
Affinity DataIC50: 413nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206274((S)-N1-(1-(cyclohexylamino)-3-(1H-indol-3-yl)-1-ox...)copy SMILES
Affinity DataIC50: 416nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206282((S)-N1-(3-(1H-indol-3-yl)-1-((3-methoxyphenyl)amin...)copy SMILES
Affinity DataIC50: 435nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206272((S)-N1-(1-(tert-butylamino)-3-(1H-indol-3-yl)-1-ox...)copy SMILES
Affinity DataIC50: 504nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206271((S)-N1-(3-(1H-indol-3-yl)-1-(isobutylamino)-1-oxop...)copy SMILES
Affinity DataIC50: 527nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206273((S)-N1-(1-(cyclopropylamino)-3-(1H-indol-3-yl)-1-o...)copy SMILES
Affinity DataIC50: 683nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206290((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-((4-(trifluorome...)copy SMILES
Affinity DataIC50: 1.29E+3nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206268((S)-N1-(3-(1H-indol-3-yl)-1-oxo-1-(propylamino)pro...)copy SMILES
Affinity DataIC50: 1.65E+3nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206269((S)-N1-(1-(butylamino)-3-(1H-indol-3-yl)-1-oxoprop...)copy SMILES
Affinity DataIC50: 1.74E+3nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed
TargetHistone deacetylase 1/11/4/6/8(Homo sapiens (Human))
Orchid Chemicals & Pharmaceuticals Limited

LigandPNGBDBM206270((S)-N1-(1-(dodecylamino)-3-(1H-indol-3-yl)-1-oxopr...)copy SMILES
Affinity DataIC50: 2.50E+4nMAssay Description:In brief, 10 μL of HeLa nuclear extract was mixed with various concentrations of target compounds (50 μL), SAHA, using 100% and none HDACs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ8Z69PubMed