Compile Data Set for Download or QSAR
Found 116 Enz. Inhib. hit(s) with Target = 'Interleukin-17A'
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50582230(CHEMBL5091495)copy SMILES
Affinity DataIC50: 0.794nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41W9TPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50578383(CHEMBL4870813)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80T6PubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50582232(CHEMBL5091603)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41W9TPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50582229(CHEMBL5080633)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41W9TPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50582227(CHEMBL5081660)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41W9TPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50582231(CHEMBL5092697)copy SMILES
Affinity DataIC50: 1.60nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41W9TPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50582228(CHEMBL5077953)copy SMILES
Affinity DataIC50: 1.60nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H41W9TPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50578382(CHEMBL4865978)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80T6PubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50578381(CHEMBL4860574)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80T6PubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50578386(CHEMBL4872143)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80T6PubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50574356(CHEMBL4845695)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:Inhibition of IL-17A in human HT-29 cells assessed as neutralization measured after 48 hrs by ELISA methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208693QPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50578385(CHEMBL4851738)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80T6PubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50578384(CHEMBL4850368)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of IL-17A in human HDF cells assessed as IL-6 release incubated for 5 hrs by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR80T6PubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50574357(CHEMBL4855085)copy SMILES
Affinity DataIC50: 4.60nMAssay Description:Inhibition of IL-17A in human HT-29 cells assessed as neutralization measured after 48 hrs by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208693QPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50574355(CHEMBL4874078)copy SMILES
Affinity DataIC50: 7nMAssay Description:Inhibition of IL-17A in human HT-29 cells assessed as neutralization measured after 48 hrs by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208693QPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50581144(CHEMBL5087050)copy SMILES
Affinity DataIC50: 9nMAssay Description:Inhibition of IL-17A (unknown origin) measured by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639TMXPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50574354(CHEMBL4866932)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of IL-17A in human HT-29 cells assessed as neutralization measured after 48 hrs by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208693QPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50574352(CHEMBL4876088)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of IL-17A in human HT-29 cells assessed as neutralization measured after 48 hrs by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208693QPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50574353(CHEMBL4860250)copy SMILES
Affinity DataIC50: 14nMAssay Description:Inhibition of IL-17A in human HT-29 cells assessed as neutralization measured after 48 hrs by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q208693QPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50573258(CHEMBL4869568)copy SMILES
Affinity DataIC50: 70nMAssay Description:Binding affinity to biotinylated human IL-17A assessed as inhibition of IL-17A interaction with 1L-17RA by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B353VPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM419139(BDBM50461078 | N-(4-ethylphenyl)-N- isobutyl-3- me...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM419139(BDBM50461078 | N-(4-ethylphenyl)-N- isobutyl-3- me...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50581142(CHEMBL3785600)copy SMILES
Affinity DataIC50: 100nMAssay Description:Inhibition of IL-17A (unknown origin) by ELISA IIMore data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639TMXPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50581141(CHEMBL5075374)copy SMILES
Affinity DataIC50: 100nMAssay Description:Inhibition of IL-17A (unknown origin) by ELISA IIMore data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639TMXPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM419256(N-(2,4-dimethylphenyl)-N- isobutyl-3-(S- methylsul...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM419252(N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonim...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50461076(CHEMBL4227214 | US10457637, Compound 124)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM419242(N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonim...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM419234(N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonim...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM419225(N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonim...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM419218(4-((((1R,5S,6S)-3- oxabicyclo[3.1.0]hexan-6- yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM419214(N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonim...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50461069(CHEMBL4228522 | US10457637, Compound 66)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM419192(N-(4-ethylphenyl)-N- isobutyl-3-(S- methylsulfonim...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50461083(CHEMBL4225889 | US10457637, Compound 62)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM419189(N-(4-ethylphenyl)-4-(((3- hydroxycyclobutyl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50461075(CHEMBL4225072 | US10457637, Compound 55)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50461066(CHEMBL4228566 | US10457637, Compound 53)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50461074(CHEMBL4227729 | US10457637, Compound 52)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM419162(N-(4-ethylphenyl)-4-((4- fluorotetrahydro-2H-pyran...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50461068(CHEMBL4228069 | US10457637, Compound 24)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM419157(N-(4-ethylphenyl)-3- hydroxymethyl-N-isobutyl- 4-(...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM419155(N-(4-ethylphenyl)-N- isobutyl-3-methanesulfinyl- 4...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM419154(N-(4-ethylphenyl)-N- isobutyl-3-methanesulfinyl- 4...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50461065(CHEMBL4225020 | US10457637, Compound 18)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50461063(CHEMBL4226803 | US10457637, Compound 8)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50581145(CHEMBL5079201)copy SMILES
Affinity DataIC50: 160nMAssay Description:Inhibition of IL-17A (unknown origin) measured by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639TMXPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50581146(CHEMBL5069442)copy SMILES
Affinity DataIC50: 190nMAssay Description:Inhibition of IL-17A (unknown origin) measured by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639TMXPubMed
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50403297(CHEMBL5288854)copy SMILEScopy InChI
Affinity DataIC50: 221nMAssay Description:The calpain inhibitory activity(I 50) was measured as ability to enter the platelet to inhibit calpain after cell lysis(assay 2)More data for this Ligand-Target Pair
In DepthDetails
TargetInterleukin-17A(Homo sapiens (Human))TBA
LigandPNGBDBM50461079(CHEMBL4227543 | US10457637, Compound 65)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:This model allows measurement of the effect of inhibitors on IL-17A secretion by CD4+ cells. The cells are frozen CD4+ cells (STEMCELL, #70026), isol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8WMGUS Patent
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